Wouldn't a pragmatic perspective be like ours - the samples are so small and the findings so marginal that nothing very much can be concluded?...
I had a look at the paper again. The B cell findings are unremarkable and we have similar studies from the past that showed nothing much. An...
It might be helpful if the document pointed out that NICE decided GET didn't even work, let alone the worries about harm!
Was there any evidence of antigenic stimulation? A few stray T cells possibly but T cells get activated by things other than antigens. Brain...
I don't see these results as leading to anything new. The studies on T and B cells are not significant with such a tiny sample. T cell...
This is an important point. At the Round Table it was made very clear that GET was not recommended because the evidence was inadequate to show...
That seems a good summary of the problem @EndME. I wonder if there is deeper confusion still. The title of paper is 'Measure of Autonomic...
Copied post This is nonsense but as a necessary upbeat take on a very costly study that was supposed to be groundbreaking it is excusable, and...
This is nonsense but as a necessary upbeat take on a very costly study that was supposed to be groundbreaking it is excusable, and at least a good...
In other words, from the outside world this looks like a non event. I think the coverage actually reflects that, in that it is all 'today's little...
I was approached by journalists saying 'This looks like a damp squib that the science community is going to forget. But maybe an opportunity to...
I think those just show how dependent rates are likely to be on recruitment routes, @Sid. Maybe blood donors aren't allowed to give blood if they...
My impression of 3e is that PWME have acquired a good sense of their fatiguability whereas healthy controls haven't a clue and are all over the...
"Some infectious diseases and cancers have been associated with the development of antinuclear antibodies, as have certain drugs." Certain drugs,...
If his agenda was to show that effort choice was down in the presence of a healthy body he would have found it convenient to note that the p value...
As far as I know positive ANA is not likely to be related to recent viral infection or viral persistence, certainly not speckled. The problem...
I doubt there is much new. Fiona Powrie used to talk about this stuff at meetings I presented at about 15 years ago. If you take away T regs in...
Yes, the usual garbling. Not even exhaustion after all? As far as I know T regs have little or nothing to do with most autoimmunity and of course...
The sample is too small to tell if they found anything in fact. And if they did it seems to me more like an 'odd smell' rather than smoke. It...
Except that this study provides no basis for such trials. It shows no evidence for a need to 'clear antigen' even if checkpoint inhibitors were...
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