I vote for introduction of the 'Perez sign': writing papers on FND is a positive diagnostic sign of: FND. It is a sign found in no other medical...
I am not sure that in this situation it is ever possible to 'know' much more. The results of the original study are out there. No information is...
I m not so sure. I have never been able to work out what the nano needle study could possibly mean. The geometry of the apparatus did not seem to...
I doubt it means very much even in the context of acute Covid, @Sasha. I cannot see any relevance to ME.
Yes, it looks like a straightforward untruth. And from what people are posting maybe one of many. In a court of law would have thought...
Yes that is a good point. I was thinking more in terms of the objective of the workshop - which I think was to bring researchers together,...
I agree with Andy. One of the big problems of online workshops is that you do not have the opportunity for private conversations - which are where...
I find this sort of 'research' pretty distasteful. It is basically snooping and snooping with the assumption that at the end of it you know how to...
I don't know much about minimally clinically important differences but the idea looks confused to me. If you have a scale from 0 to 1 in roughly...
No, it is fine. As long as I know it isn't going to go into a viral spiral!! Which I know it won't.
Well, I would hope that nobody claims to have a comprehensive understanding of that, especially when we are talking of very heterogeneous...
I agree that if anti-DC8 has not been given to humans yet a safety focused trial is in order. But I would expect it to be possible to do a primate...
The list looks a bit like a second hand impression of what someone has heard, as I think you are suggesting. My question would be why is someone...
I don't know. I suspect that drug companies had cold feet and no independent academics have had the sense to give it a go.
Depends on whether you think 1 in 30,000 is common. I am not so sure.
That is an interesting document but if I remember rightly it was put out by Genentech at the time when rituximab was made available for RA....
OK, but in general the side effects of rituximab are nothing like ME. ME patients may well get PEM from the rigmarole of having an infusion, so I...
A trial of anti-CD8might be the simplest option. If it did nothing with CD8 depletion the idea would be refuted fairly effectively. DecodeME is...
You might but might not. A T cell overenthusisam mechanism could be tripped stochastically by anything and not have a genetic link. Itmight, but...
Maybe just an anti-CD8 antibody to reduce CD8 activity generally. It would be interesting to know what has been established about the specificity...
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