I cannot see any results for controls in the cytokine paper?
I have not looked through that paper in detail yet but one thing looks to me to be glaringly missing. They talk of a correlation between fall in...
I am afraid that doesn't look like evidence @Arisoned. When a cluster of private physicians with a special interest in a diagnostic category that...
Something as simple as that might be brilliant. A barely noticeable locket on a fine gold chain (that looked good if it showed) and just monitored...
As a rule yes, JemPD. If 20% of subjects leave their Fitbits in a drawer for the last 3 months it doesn't matter as long as they really don't know...
Thanks JemPD. I think I would enlarge on the point made to Trish, that inconsistency needn't be seen as an insuperable problem. In most...
Good points, Trish. I have never been terribly attracted to crossover trials and tried to think why. (Presumably they may give more data from...
I have come around to thinking that a high quality LDN trial for ME must be done. I don't feel I should give a running commentary on the Working...
I agree that there are various aspects of the LDN story that have an alternative medicine ring about them and might be convenient if wanting to...
I had a look at that and was not impressed that there was anything other than speculation involved. If we do not even know its a drug works it is...
This is what one keeps hearing but it is interesting to consider how the physicians ever came to know this was the right thing to do. It is easy...
The thermostat analogy is indeed a no-brainer, but we can all think of that, and the reasons why it might be right or wrong. It only gets...
Absolutely. I am afraid that to me multi systemic dyshomeostasis sounds about as hand-waving as biopsychosocial. If a thermostat misbehaves...
Why should anybody want to do it? You might as well study washing your ears out with turps or sitting on a cold floor for 3 hours. This is the...
Seems to be just some stories on the net of wonder cures, isn't it? People like to believe in these things it seems, but I haven't seen any reason...
No, research assessment exercises do not go back to see if your paper in a top journal proved unreplicable. Did any of the PACE authors get fired?...
If it is a good thing to inhibit an inflammasome then it is likely to be more use using a drug tailored to doing that rather than some obscure...
I don't think we can assume anything because at present we have no reliable evidence of any particular mechanism. You need to be aware that a...
Acclaim, basically. Every scientist wants to be seen as a groundbreaker. The pressure to produce high impact work is also great. You don't get...
I think it is the other way around. Standards of ethics committees have probably fallen with commercialisation of the research ethic.
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