That looks a fairly good account of why oxaloacetate isn't going to do anything. It also looks like fairly good account of why this is almost...
On some days politics is existential! But so is tennis today and there's no rule against tennis is there? Nadal for champion!!! And that Ons lady...
This seems to me quite a good outcome. Javid was a good person to get an appropriate ME advisory group together but having said that he did not...
Maybe the doctors are too and the clinics cancelled.
I think effect sizes are for something different. They are crucial but not related to primary outcome. Maybe we should take four scenarios with...
Only if a trial is the single final arbiter of whether or not a treatment is to be judged useful. In reality trials are very rarely in that...
If Berlin Cures are right the test is probably no use in any situation - i.e., if it does not pick up antibodies reliably. I suspect it is more...
Breath tests are done by gastroenterology units on the NHS. But as a caution, read the paper attached - or abstract. The reliability of these...
This is IiME territory - they might have local contacts.
I don't think that is right @Snow Leopard. In my phase I study of rituximab in RA the primary outcome I chose was C-reactive protein because I...
This looks very problematic. To be robust the method has to make sure there is no way attitudes can influence. If bias is possible it will almost...
A primary outcome measure has to reflect reliability as well as directness. If a direct measure is totally unreliable it is not suited to being a...
From the abstract it looks as if the authors do not understand the process of choosing a primary outcome measure. The result looks pretty...
It isn't clear from the abstract whether the initial MRI findings predicted fatigue improvement or that the change in MRI over 6 months correlated...
It is likely that a small proportion of people diagnosed with ME in fact have an autoimmune disease. But equally, people often get given diagnoses...
Not particularly, the pattern of incidence with age is not similar to autoimmune disease in general. Some autoimmune diseases have odd age...
I spoke to an academic haematologist with expertise in clotting today. They had not heard of any of the Pretorius work or the methods being used....
Such things are a thing of the past, I fear. Everyone at the top has lost the plot since the introduction of the 'internal market'. Fortunately...
I think UC has symptoms that sound very like ME, but the key thing about the cycles of symptoms in ME is that they do not seem to relate to any...
This is a distraction, just as Trish says, but I think the metaphor was in use way before 2014. I wonder if it was hijacked by feminism. I have...
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