I very much agree with Simon's analysis. This study may show an abnormality of signalling that, maybe amongst other things, is involved in...
What is not clear is what advice might be of help that is not already being implemented. If MEAction want to support PWME they would do well to...
Another approach would be to say that serum samples before and after treatment would be stored and if a convincing positive result obtained these...
I would be very happy to advise on a draft protocol.
I am not clear quite why Nicola wants an 'inflammatory panel'. There is no evidence at present for any measurable inflammation linked to ME...
I think you are being far too generous. Reliable tests don't have disclaimers like this. They don't need them. Tests used in research are...
I think that may just be James Coyne being unclear, as he often is.
Just that a report like that screams 'Hi, guys, here's a bogus report for you'. If a test is not suitable for clinical use you do not release it...
Chiefly because the immune system isn't inside the brain, even if sometimes it has effects on the brain.
I am pretty sure this is pseudoscience. Intracellular electrical capacity in lymphocytes means nothing at all as far as I am aware. Note that the...
Maybe but that paper basically says: Results: LongCovid symptoms bore no relation to FND, being rather things like headaches and ageusia, and try...
An honest attempt at gathering data has to include making sure the results are not misleading. If the basics of scientific method are not clear to...
I have not gone through the paper in great detail but like Hutan I think there may be problems with it. One thing that is strange is that only...
What TG says in the tweets seems reasonable to me. She is surprised by the lack of literature on microclots if they are an important finding. I...
I have never heard of BMC Rheumatology as a journal. Skimming, this looks like an article pushing a politically correct point about patient...
I think the point is that there is a group of people with striking neurological symptoms like seizures or tremors or twisting movement disorders...
FND refers to a real group of people, mostly with seizures and movement disorders. It may be a silly diagnosis but the people and symptoms are...
The mean age of ME/CFS patients dying from heart failure, 58.7 years, was significantly lower than the age of those dying from heart failure in...
CD68 is a general macrophage marker. CD169 probably equates to active scavenger macrophages with antigen-presenting capabilities. I am not sure...
Studies of this sort are likely to accrue all sorts of biases in the groups of patients studied, depending on what clinics they were drawn from...
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