Interesting case. They say: Fatigue may be present already without any physical activity or only in association with physical exercise. The latter...
Yes, I found it a bit dated and lacking practical insight. The senior author Leemon McHenry I know from my philosophy world. A very nice guy,...
The other thing is that 'evidence-based' is nearly always rolled out when things are suspect - 'but we can assure you that our treatment is...
They acknowledge this but I am not convinced they have guarded against it well enough.
Can you explain that in plain English. What would be obvious? Surely we only 'know' about what happens in standard situations with healthy...
Interesting to see this paper. The points that strike me: 1. The increased association with NHL is not that great at 1.29. It is potentially of...
I don't follow that. If it shows up on the graphs as the result that we see then it does. I realise things are complicated but as far as I can see...
Are you sure? It seems to me a bit odd to do a CPET two days running to show reproducibility. I would expect in the context of ME to leave it for...
When I have flu I don't actually have a choice. I collapse shivering if I try to do anything vigorous. But my point was exactly this - that to...
That sounds a bit weird. I thought the post of doing it twice was to show a difference?
Another interesting example of the CPET not correlating with PEM in time scale - but the other way around. I go out of my way to be sceptical...
Yes, I agree with all your points, but there remains the key point that if we are tracing a complex series of cause-effect interactions then it is...
Agreed. And I can see the logic of the original experimental design trying to show a dip in function on day 2 by looking for maximal performance...
Actually I don't think I could. I think I would vomit and collapse on the floor. Over the years I have looked after people in hospital with all...
I think this is highly possible and I think it is worth discussing in the context of this study. I understand the desire to keep discussions in...
Absolutely, I do hope someone takes this on. I heard yesterday that my wife's cousin has an app linked to a sensor in her ski boots that tells...
But wouldn't they then be considered to have PEM? My understanding is that the reason for doing a 2 day CPET in ME is because it is expected to...
It is isn't a matter of doubting willingness to do the test properly. It is recognising that if you are feeling ill you may be in a mental state...
Yes, I guess that if ATA 188 worked it would suggest that MS lesions are specifically mediated by EBV infected cells. But it would be a pretty big...
It looks fatuous. People having trouble after Covid are defined as people having trouble after Covid that isn't something else. It is a bit like...
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