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  1. J.G
    Post

    Aripiprazole - Abilify

    I can't answer your other questions, but figuring out why and how Abilify seems to be beneficial to (a subset of) pwME is an area of active...
    Post by: J.G, May 22, 2021 in forum: Drug and supplement treatments
  2. J.G
    Post

    MEAction 2021 MECFS researchers video with R Davis,Prusty

    That's correct. Three out of five IDO2 mutations that Dr Phair identified in his metabolic trap presentation(s) are on the 23andMe v4 chipset....
    Post by: J.G, May 16, 2021 in forum: ME/CFS research news
  3. J.G
    Post

    MEAction 2021 MECFS researchers video with R Davis,Prusty

    Quite right. "Publish or perish" is a common turn of phrase in academia. Gotta meet your quota of peer-reviewed published papers or risk losing...
    Post by: J.G, May 13, 2021 in forum: ME/CFS research news
  4. J.G
    Post

    frontiers in Medicine - Theory: Treatments for Prolonged ICU Patients May Provide New Therapeutic Avenues for ME/CFS - Stanculescu, Bergquist et al

    The more I look at this paper, the less I know what to make of it. HPA axis* dysfunction and oxidative & nitrosative stress are (very) old ideas...
    Post by: J.G, May 9, 2021 in forum: ME/CFS research
  5. J.G
    Post

    Aripiprazole - Abilify

    That's fantastic! Carpe diem! (Well, you know, within the limits of your energy envelope!)
    Post by: J.G, Apr 27, 2021 in forum: Drug and supplement treatments
  6. J.G
    Post

    Aripiprazole - Abilify

    How are things, @leokitten ?
    Post by: J.G, Apr 26, 2021 in forum: Drug and supplement treatments
  7. J.G
    Post

    Aripiprazole - Abilify

    @Jessie 107 @chelby Hope you're both doing okay! We've not heard from you in a little while. How are your Abilify trials going?
    Post by: J.G, Feb 28, 2021 in forum: Drug and supplement treatments
  8. J.G
    Post

    Are Circulating FGF21 and NT-proBNP promising novel biomarkers in ME/CFS, 2020, Joan Charles Domingo et al

    They are indeed. FGF-21 - I was told in writing - is under ongoing investigation as a potential biomarker for certain mitochondrial disorders...
    Post by: J.G, Dec 24, 2020 in forum: ME/CFS research
  9. J.G
    Post

    Are Circulating FGF21 and NT-proBNP promising novel biomarkers in ME/CFS, 2020, Joan Charles Domingo et al

    My serum FGF-21 was tested some three years ago by a London, UK immunology lab as part of a study on mitochondrial dysfunction. My serum FGF-21...
    Post by: J.G, Dec 23, 2020 in forum: ME/CFS research
  10. J.G
    Post

    Liquid chromatography-mass spectrometry .. reveals increased levels of tryptophan indole metabolites in .. metabolic syndrome, 2020, Wrobel et al

    I'll take to answering my own question! :jimlad: I don't see how it does. The MetS study finds enrichment of indole pathway metabolites in urine,...
    Post by: J.G, Dec 16, 2020 in forum: Other health news and research
  11. J.G
    Post

    Liquid chromatography-mass spectrometry .. reveals increased levels of tryptophan indole metabolites in .. metabolic syndrome, 2020, Wrobel et al

    Does it? How?
    Post by: J.G, Dec 11, 2020 in forum: Other health news and research
  12. J.G
    Post

    Multi-omics Examination of Q Fever Fatigue Syndrome Identifies Similarities with Chronic Fatigue Syndrome (Preprint, 2020) Raijmakers et al.

    Interesting. This is a Dutch study. The Netherlands experienced a "Q Fever epidemic" (link) between 2007-2011. Some 20% of patients went on to...
    Post by: J.G, Nov 29, 2020 in forum: ME/CFS research
  13. J.G
    Post

    Aripiprazole - Abilify

    Hmm. Abilify does not eliminate trapped cells' elevated tryptophan content, so it cannot push a patient out of the trap. Abilify also does nothing...
    Post by: J.G, Nov 29, 2020 in forum: Drug and supplement treatments
  14. J.G
    Post

    Aripiprazole - Abilify

    @Sid I know, I know. My point is that all dopaminergic drugs are not equal, and your friend's experience with bupropion can therefore not...
    Post by: J.G, Nov 28, 2020 in forum: Drug and supplement treatments
  15. J.G
    Post

    Aripiprazole - Abilify

    I'm sorry to hear that. Important caveats though are: - Abilify is a serotonergic drug as much as a dopaminergic drug; - Even within the subclass...
    Post by: J.G, Nov 27, 2020 in forum: Drug and supplement treatments
  16. J.G
    Post

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    It's no clearer in the original language (Dutch), most likely because the main article is effectively one long citation that seems to use the...
    Post by: J.G, Aug 28, 2020 in forum: ME/CFS research news
  17. J.G
    Post

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    Gosh, the article by Dutch newspaper AD is a tricky one. It does not use the word degenerative ("degeneratief"), nor does it explicitly describe...
    Post by: J.G, Aug 28, 2020 in forum: ME/CFS research news
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