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Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes Published: September 14, 2022 [Line breaks added] Highlights • Public release of gene-based association statistics for 4,529 diseases and traits • Genebass, a browser...

Here's an attempt to bring together all of the main candidate genes from different sources: Tier 1 genes, tier 2 genes, genes significant in MAGMA, and the gene (or two genes if it is not clear) closest to a locus for the top 25 loci. Sources: Tier 1 and 2 genes: Candidate genes document...

3603 Multimodal non-invasive neurophysiological testing of small fibre neuropathy in long COVID Anthony Khoo, Kisani Manuel, David Lynn, Maria Crotty Background Long COVID is associated with a diverse range of debilitating neuropathic and autonomic symptoms that may indicate small fibre...

Interesting that in this meta-analysis, there actually is a significant gene set enrichment in MAGMA: GOCC_GLUTAMATERGIC_SYNAPSE Paolo commented this on ME/CFS Science Blog's blog about overlapping controls, so I'm not sure how much impact this may have had on the results: I don't know enough...

Oh weird. On Firefox for Android, it's redirecting to the homepage of MSN. But every other browser, it seems to work. Thanks for adding the other link.

FYI, the MSN link doesn't seem to go to an article.

Note that your link goes to the paper the HLA data comes from, which happened before DecodeME, but the text says the title of the thread's paper. Anyway, it looks like the reason they didn't genotype HLA-DQA1 and other loci is that for data on healthy controls, they used the results of an...

Characterizing post-COVID-19 syndrome in multiple sclerosis: Vaccine status, infection burden, and therapy categories as predictors Deepak Sharma ∙ Christian P. Kamm ∙ Robert Hoepner ∙ Iris-Katharina Penner ∙ Thomas Nyffeler ∙ Lara Diem [Line breaks added] Background Post-COVID-19 syndrome...

Maybe specifically EBV-infected B cells? Just to pull from lupus research again, these authors think EBV may be necessary for lupus: The toll like receptor 7 pathway and the sex bias of systemic lupus erythematosus, 2025, Frontiers in Immunology

Comment on “Pre-pandemic diabetes and risk of long COVID: Longitudinal evidence” Ali Madad Haq Published: 23 October 2025 Main points: Web | PDF | Journal of Diabetes & Metabolic Disorders | Open Access

Pre-pandemic diabetes and risk of long COVID: longitudinal evidence Yusuff Adebayo Adebisi, Anas Ali Alhur, Najim Z Alshahrani, Victor C Cañezo Jr, Edgar G Cue, Don Eliseo Lucero-Prisno III [Line breaks added] Objective To examine whether pre-pandemic diabetes is associated with an increased...

I don't know if this needs its own thread, but this chapter, from the book 'The Palgrave Handbook of Third-Wave Psychotherapies', is written by Fiona McKechnie, who is affiliated with Bristol ME/CFS Service, according to the journal. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long...

Now published: Neurometabolite alterations in Gulf War Illness: a whole-brain magnetic resonance spectroscopy study, 2025, Jones, Younger et al

Neurometabolite alterations in Gulf War Illness: a whole-brain magnetic resonance spectroscopy study Chloe Jones, Olivia Haskin, Jarred Younger [Line breaks added] Abstract Gulf War Illness (GWI) affects approximately 30% of veterans who served in the 1991 Persian Gulf War and is...

Oh thanks that makes sense. I see that lots of the examples on the beeswarm page are in bins with ties.

I saw they updated the plot to remove the error of 6 positive green dots. But it looks to me like the data is not identical to the previous version. Here is the new figure 2A: I overlaid the new plot over the old plot to compare the y values of the dots. The new ones are to the right, for...

Also in Precision Life's long COVID study: Genetic Risk Factors for ME/CFS Identified using Combinatorial Analysis, 2022, Das et al Genetic Risk Factors for Severe and Fatigue Dominant Long COVID and Commonalities with ME/CFS Identified by Combinatorial Analysis, 2023, Taylor et al But it...

I saw that TASL is also involved in lupus. Just some quotes I grabbed very quickly from abstracts: TASL has a key role in SLE, Nature Reviews Rheumatology, 2025 The role of TASL in the pathogenesis of SLE: X marks the spot, Annals of the Rheumatic Diseases, 2020

Ha thanks. I'll keep reading my intro to genetics book. I do think AI will be providing insights in the future because it already is now. AI means many different things. Precision Life, that works on ME/CFS genetics, says their tools are based on AI. DecodeME even used a machine learning...

Post about World ME Alliance's new resource collection moved to a new thread: Medical Education Hub - World ME Alliance