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  1. Sean

    Mind and Body in the Guardian again

    Even more. Because it is so much more unfalsifiable, and hence much harder to refute. Psychologisers have an endless supply of arbitrary re-framings to play whack-a-mole and use to hang onto their power. The software/hardware analogy simply does not apply to wetware (biology). They are...
  2. Sean

    Clare Gerada: influence on UK medical practice and ME/CFS management

    The golden age of psycho-tyranny has begun.
  3. Sean

    Review Beyond physical exhaustion: Understanding overtraining syndrome through the lens of molecular mechanisms and clinical manifestation, 2025, Fiala et al

    The phenomenon of over training in otherwise healthy people strongly suggests to me that ME/CFS patients are dealing with unrelenting pathological physical demands that produce results which have a lot in common with extreme over training. The difference being that the cause of over training is...
  4. Sean

    Understanding Chronic Fatigue Syndrome – Workshop with Dr Bruno Silva [North Staffordshire Combined Healthcare NHS Trust]

    Or, there is simply a sampling/reporting bias in those who persist in trying to figure out what the problem is, as opposed to those who, for whatever reason, do not and just try to survive it all. He got this very critical point right.
  5. Sean

    Shingles vaccines, chickenpox, Shingrix

    Reaching into the memory banks on this one, but I think that protective effect applies mainly to females, less so for males.
  6. Sean

    Review Effects of traditional Chinese mind-body exercises for patients with chronic fatigue syndrome: A systematic review and meta-analysis 2023 Kong et al

    Tai-Chi seems to me among the most optimal and safe forms of general exercise, and I did give it a good go about 20 years back. But its effects on my ME/CFS was no different than any other form of exercise or physical activity, however gentle and carefully titrated. Also tried yoga 35 years...
  7. Sean

    The effects of exercise on dynamic sleep morphology in healthy controls and patients with chronic fatigue syndrome, 2013, Kishi et al

    I have had that at various times. Especially early on, not so much any more. Might be in part because of getting old (early 60s).
  8. Sean

    Review Dietary Supplementation for Fatigue Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)—A Systematic Review, 2025, Dorczok

    Conclusions: Though some DSs showed potential in reducing fatigue in ME/CFS, methodological limitations and inconsistent results hinder definitive conclusions. Take note, psycho-behaviouralists.
  9. Sean

    News from Aotearoa/New Zealand and the Pacific Islands

    :facepalm::grumpy:
  10. Sean

    Brief Outpatient Rehabilitation Program for Post-COVID-19 Condition, Nerli et al, 2024 - with comment from T. Chalder

    Propaganda works. And sometimes the more blatant and shameless it is, the better it works.
  11. Sean

    Impacts of the 2024 change in US government on ME/CFS and Long Covid

    Yep, the devil is in the detail. The best predictor of someone's future behaviour is their past behaviour, and his track record is,... not encouraging.
  12. Sean

    Clare Gerada: influence on UK medical practice and ME/CFS management

    This is the real madness. The attention and focus, which really means funding, should be on a needs and demonstrated benefit basis. Not on some arbitrary we must give both equal billing basis for fear of being accused of anti-psych prejudice, and because it gives us an excuse not to properly...
  13. Sean

    Placebo effect discussion thread

    IIRC, for pain it is not clear as the effect sizes are all over the place. Also is not clear if it is an actual placebo effect taking place, or is a whole other bunch of methodological confounders that are not being properly controlled for, and are all just being placed in the placebo basket...
  14. Sean

    If ME/CFS research got £1 billion, what would stop it being wasted?

    Any condition that has diagnostic criteria requiring a 50% or greater reduction in activity capacity is already imposing a serious loss of function. More than enough to make a patient uncompetitive in the labour market. Let alone factoring in having to try preventing further deterioration...
  15. Sean

    Impacts of the 2024 change in US government on ME/CFS and Long Covid

    This is not good. But my bigger concern is if the current US admin tries to permanently destroy research records and data. That really will be an unrecoverable situation. It is the difference between hitting pause on research, and having to rebuild research programs from scratch. Data in...
  16. Sean

    Mind and Body in the Guardian again

    Therefore does not need any further research of any kind on it that might show an alternative explanation, especially biomedical. Who needs falsification? That way only leads to lofty eminence being called into question.
  17. Sean

    Mind and Body in the Guardian again

    I have had prescription glasses that worked noticeably better when I slightly tilted the angle of the lenses relative to the face. In this case by raising the frame arms 2-3mm at the ears with some wraps of elastoplast type tape. But the arms on most frames can be adjusted too. I don't think...
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