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  1. V.R.T.

    Can Large Language Models (LLMs) like ChatGPT be used to produce useful information?

    Again, a lot like humans!
  2. V.R.T.

    Can Large Language Models (LLMs) like ChatGPT be used to produce useful information?

    Some of these posts have been moved from the DecodeME preprint thread. Yeah LLMs are very good at confidently spouting bollocks.
  3. V.R.T.

    Preprint Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome, 2025, DecodeMe Collaboration

    Well the AI is really raining on my parade today! Lets hope its confidently incorrect on that front (not that I expect a drug tomorrow, nice as that would be...) It's weird though, I searched the preprint for drug, treatment and theraputic and only really found this phase claiming that the...
  4. V.R.T.

    Criticisms of DecodeME in the media - and responses to the criticisms

    This is a very good point.
  5. V.R.T.

    Criticisms of DecodeME in the media - and responses to the criticisms

    And, it seems, large meticulous genetic studies can be ignored also. Facinating what it's possible to ignore if your faith in the almighty psychobehavioral paradigm is strong enough. Almost inspiring.
  6. V.R.T.

    Criticisms of DecodeME in the media - and responses to the criticisms

    Yes I think they are trying to hold back the tide by painting this study as much more insignificant than it is, saying 'well we are still light years away from having any idea what is causing this' etc...
  7. V.R.T.

    Genetics: FBXL4

    Have we seen this gene before in ME/CFS research? Or am I just thinking of the Crawley pediatric LC study?
  8. V.R.T.

    Open Norway: Plasma cell aimed treatment with daratumumab in ME/CFS (ResetME) - Haukeland University Hospital

    Drat. Hopefully F&M can raise the funds some other way then.
  9. V.R.T.

    Genetics: BTN2A2 and BTN3A3

    Understood. I certainly didn't think this gene was a definite slam dunk, just something that maybe strengthened the argument for JEs hypothesis. I hadn't realised that the IFNG/CD8 T CellI element was just from that one mouse model paper though. It would be interesting if we could come up with...
  10. V.R.T.

    Open Norway: Plasma cell aimed treatment with daratumumab in ME/CFS (ResetME) - Haukeland University Hospital

    So, the 22 million kroner question is: do the DecodeME results strengthen the case for using Daratumumab?
  11. V.R.T.

    Genetics: BTN2A2 and BTN3A3

    It has a certain appeal! It sounds like something from an old sci fi film. This does all look rather relevant to your hypothesis, unless I'm very much mistaken?
  12. V.R.T.

    Preprint Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome, 2025, DecodeMe Collaboration

    Iirc they are actually planning a GWAS with Lipkins lab
  13. V.R.T.

    Genetics: CCPG1

    Could you possibly expand on this a little? You've mentioned this idea before but I can't get my head around it.
  14. V.R.T.

    Criticisms of DecodeME in the media - and responses to the criticisms

    :sick::emoji_rage: They seem to have a gameplan in place. I think it will be hard to counter until these findings are built upon sadly.
  15. V.R.T.

    Donate to build on the work of DecodeME

    Does anyone have an opinion where the best place to donate currently is? Like through AfME or directly to Chris Ponting's lab? I understand the final pieces on finalising this study will be done by Chris and a small team on limited funding so maybe that is the best place to donate initally? Or...
  16. V.R.T.

    Genetics: BTN2A2 and BTN3A3

    As we discussed in the preprint thread, the fact this is downregulated and it inhibits CD8 T cells and IFNG might be relevant to JE et al's hypothesis and related theorising.
  17. V.R.T.

    Criticisms of DecodeME in the media - and responses to the criticisms

    Harriet Martineau, Alice James, Virginia Woolf at points...
  18. V.R.T.

    USA: The RECOVER Initiative - Long Covid research

    Maybe i should reply on bluesky but LDN and Baricitinib are already being thoroughly trialed (although I guess LDN is being trialed in ME). GLP1 is an interesting idea I suppose, not sure what the rationale is. As for SGB, I am really skeptical, but I suppose it's better to have a trial than not...
  19. V.R.T.

    Criticisms of DecodeME in the media - and responses to the criticisms

    Statistically, I think it's likely some of them are.
  20. V.R.T.

    Preprint Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome, 2025, DecodeMe Collaboration

    Strep triggered me and my partner's illnesses too.
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