Did you know that when Willy Burgdorfer was running labs on samples he was shipped from Long Island, NY, in which he would eventually discover the spirochete the world identifies with Lyme, close to 100% of all the patient samples he looked at tested positive for a ricketsia? The results were so...
Does Bb cultured in blood suggest an artifact? Besides, you won't find many knowledgeable Lyme patients who like any form of the first tier, IFA or other. But that's what the Lyme gamekeepers prescribed decades ago with a puzzling algorithm, so an entire generation has been stuck with it...
Just remember, Dapsone comes with potential baggage. I seem to recall Hemolytic anemia possibly being one, for example. H suggests limiting treatment duration to,hmm, I don't remember. But not long. It's been my experience (personal and relayed) that some clinicians shrug off those constraints...
One thing I've learned over way too long is that research-smarts is not necessarily the same as clinical-smarts. In many ways they are cross-elastic and overlap. Sometimes, however, they can be divorced from one another. I love reading the research, but I often take findings with a grain of...
Antibody titre, off and on. Most of the time I test negative. I can usually anticipate a flare as I test positive for hemolyitic anemia just before I do. I've tested microti-positive through Mayo and the NIH, so, eh, pretty good facilities.
Treatment? Yes, I cannot remember what I took, though...
Don't think TBE is in the US. But these symptoms noted in the article could - I'd think - ring a bell with many in this forum. Unlike the 3 B's, TBE is caused by a virus.
If you test positive for duncani then you're automatically excluded. Check out exclusions. One is if patient is infected with any other tick-borne disease.
Both b duncani and microti may run chronic, at least as far as I can deduce. There is some positive news purportedly for sufferers of long term b microti, but even then, you'll probably know treatment recommendations are a minimum of six weeks, and that with a tier 3 drug, and no guarantees...
How could they not get 24 Lyme patients when Columbia is literally surrounded by areas that can be characterized not merely as Lyme endemic, but arguably Lyme epidemic? You've Connecticut to the northeast, Long Island to the east. New Jersey and PA to the west.
Puzzling.
As an aside, but uncomfortably related matter: My wife just got a new pacemaker defibrillator. It comes with a wifi monitoring device that somewhat resembles Amazon's Alexa. She was told to leave it on 24/7 so they could always have her monitored. She protested on invasion of privacy grounds...
Sometimes I think medicine is etch-a-sketch art. You can create whatever picture suites you at any given moment, then erase and start over with an altogether different picture.
If history stands for anything, I suspect that is what will happen with LC. Once the pandemic is truly in the rear...
I must admit I am not up on my Covid research. But if Covid is potentially securing priviledged sites in tissue, and it cannot easily be found in serum, short of biopsies (hit or miss since we've no way of knowing yet what preferred tissue might be), or autopsies (these days far from a given)...
"We anticipate that the most common sequelae to COVID-19 will be a postviral fatiguing syndrome and its persistent mix of somatic and psychiatric complaints in the absence of a clearly observable cause."
Small wonder. What do they mean "in the absence of a clearly observable cause?" I was...
Seems to me there is an argument to be made for a correlate, a cognitive one. TEMMA: The Theory of Effort Minimization in Mental Activity. If there were, I would subscribe to it. I do my best to minimize concentration, strong emotions, math, judgement...I do not mean this ironically. I pay a...
Welcome, @5vforest ! I think Fallon's NIH excursion was slated to wrap up early this Spring. I'm not sure if covid has caused delays.
The good news is it's a structured study. Bad news is I think it's on the small size, like 24 or so patients. With an annual infection count in the US alone...
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