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  1. Sean

    Preprint The Potential Causes Of Myasthenia And Fasciculations In The Severely Ill Me/Cfs-Patient: Role Of Disturbed Electrophysiology, 2025, Wirth et al.

    I used to get these quite a lot early on, mainly in the thigh muscles. Not so much anymore since I got better at overall management.
  2. Sean

    Embodied wisdom: towards acceptable and helpful explanations for functional somatic symptoms, 2025, Saunders et al

    Exactly. All this extravagant rhetorical window dressing just to avoid having to say: 'We don't know. We got nothing.' Nothing new under the BPS sun indeed.
  3. Sean

    General thread on functional disorders in Sweden

    i.e. How to more effectively lie to patients, entirely to avoid the liar facing up to the stark appalling fact that they actually have no explanation and no treatment to offer. This should be a formal crime, and a very serious one.
  4. Sean

    Heightened innate immunity may trigger chronic inflammation, fatigue and [PEM]…, 2025, Che, Hornig, Bateman, Klimas, Komaroff, Lipkin+

    Always within normal for me, including annual routine bloods. (Occasionally get a borderline number, but always settles back to within range by the following year's sample.) Only consistent significant result I get is persistently high ALP, since at least my mid-20s, typically in the 130-160...
  5. Sean

    Open Medicine Foundation (OMF)

    Yes, some Americans, not all.
  6. Sean

    The health and economic burden on family caregivers of persons with me/cfs diagnosis: a register data study from Norway, 2025, Kielland et al

    So why not say it that way? It isn't a big deal, and might just be translation or second language issues. But it reads oddly to me.
  7. Sean

    Open Medicine Foundation (OMF)

    A tip from an Australian to the fund seekers: We don't do hustle culture here. We hate it, actually. Selling yourself so overtly and in such gushing language, as Americans tend to do, just turns us off. We might superficially share the same basic language, but we use it very differently at times.
  8. Sean

    United Kingdom: News from #There for ME

    I am with those who have very deep concerns about any service provided or informed by the old guard. They simply need to be completely and permanently removed from the entire process. My trust levels in the current medical system on handling ME/CFS are also at rock bottom, effectively zero. I...
  9. Sean

    A longitudinal evaluation of gastrointestinal symptoms in children with autism spectrum disorder, 2025, Wu Nordahl et al

    A rigorous symptom classification was performed by physicians via clinical consensus. Not sure those two ideas fit together well.
  10. Sean

    Brain chemistry reveals psychiatry’s false divisions – new study

    If the brain (and mother nature) does not respect diagnostic boundaries, neither should our treatments. Sounds awfully transdiagnostic. Which is a concern.
  11. Sean

    [CBT] for Cancer-Related Fatigue: A Comparison Between Patients Treated With Curative Intent and Patients With Advanced Cancer 2025 Knoop et al

    The two groups differed significantly at baseline on fatigue-perpetuating factors, but not on fatigue severity. So what is the relevance of the 'perpetuating factors'?
  12. Sean

    "...I'll take whatever you want, as long as it helps" Nutrition talk for people with ME/CFS in group fitness, 2025, Keurulainen (in Finnish)

    Oh, it's evidence. They have just got the interpretation of the evidence completely wrong.
  13. Sean

    Protocol Early identification of functional somatic disorders in an internal medicine diagnostic clinic: The DISTRESS trial 2025 Madsen, Fink et al

    Talk about giving the game away. Their project is entirely about forcing us to submit, independent of any justification, and conning the rest of the world into believing that they should be allowed to do so, and that any failure of their project is entirely our fault. Psychosomatics blew clean...
  14. Sean

    Opinion Nociplastic pain: controversy of the concept

    If ever. Must be nice to be able to deal yourself the perfect get-out-of-jail-free card whenever reality gets a little too close for comfort.
  15. Sean

    Reconstructing Psychopathology: A Data-Driven Reorganization of the Symptoms in the Diagnostic and Statistical Manual of Mental Disorders, 2024,Forbes

    We also mapped some exemplar DSM-5 disorders onto our hierarchy; some formed coherent syndromes, whereas others were notably heterogeneous. Maybe I am an idiot, but I completely fail to see how a mere consistent grouping of symptoms establishes a unique discrete entity with underlying...
  16. Sean

    Transdiagnostic approach to understanding persistent physical symptoms, 2025 Chalder et al

    and high healthcare costs. Guess who their real target audience is in these studies. As always.
  17. Sean

    Personality Profiles Among People With Functional Motor Disorders 2025 Cucco et al

    I think studies like this are inherently scientifically meaningless. They are rigged from the start by the underlying assumptions about 'personality' and its causal role. The whole field is dangerous junk.
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