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https://www.bbc.co.uk/news/articles/c4g7722wxj4o [Excerpt] An Exeter-based research firm has developed what it believes is a "world first" breakthrough test to help confirm the existence of long Covid in some patients. Attomarker, which specialises in health diagnostic technologies, said it...

Abstract Background Self-reported health problems following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are common and often include relatively non-specific complaints such as fatigue, exertional dyspnoea, concentration or memory disturbance and sleep problems. The...

I don't think FND overlaps with ME/CFS to a degree that warrants the former's inclusion in this document, and I think it's a mistake to put it in there. Aside from PEM, there's a distinct immunological component to ME/CFS — the source of 'malaise', sore throats, tender lymph nodes, etc. This...

Is it still in there? Does anyone have a downloadable copy of the course?

He seems to have been a clinical biochemist in Oxford, and has a personal interest in pain research.

Relief in just 1 in 10 patients seems staggeringly low, but the tone of the paper doesn't seem to convey this.

Abstract Objectives To summarize and evaluate Cochrane reviews of pharmacological therapies for adults with fibromyalgia syndrome (FMS) pain. Methods Systematic search of Cochrane Database of Systematic Reviews to May 2024. Generic quality assessment used AMSTAR-2 criteria, validity checks of...

These titles are getting wilder.

It doesn't look super convincing.

This seems to suggest that ~20% of the RECOVER cohort had PEM but did not meet ME/CFS criteria. And that ~11% of the cohort have ME/CFS owing to COVID-19, yet don't have long covid...?

I don't understand how this paper has defined long covid. "Our inclusion criteria are as follows: (1) human study population with confirmed COVID-19 diagnosis through polymerase chain reaction (PCR) test, antibody test, or a clinical diagnosis; (2) index date of first test/diagnosis, date of...

Abstract Importance Updated knowledge regarding the global prevalence of long COVID (or post-COVID-19 condition), its subtypes, risk factors, and variations across different follow-up durations and geographical regions is necessary for informed public health recommendations and healthcare...

Article about a woman with ME/CFS and diagnosed CCI and tethered cord. https://www.thesun.co.uk/health/32671565/mum-skull-spine-daughter-nursery-glandular-fever/

The first few sentences of this paper put me right off, as does the tweet about 'groundbreaking work' from one of the authors. These are supposed to be ME/CFS experts. Do they really think you only get PEM after being on a treadmill, or is it the case that the authors write poorly....? Who knows!

Abstract Chronic muscle fatigue is a condition characterized by debilitating muscle weakness and pain. Based on our recent finding to study the potential effect of mTOR on ATG13 inactivation in chronic muscle fatigue, we report that biweekly oral administration with MHY1485, a potent inducer of...

The GP leaflet links to a 'PESE booklet', which is available here: https://www.shu.ac.uk/advanced-wellbeing-research-centre/projects/an-information-booklet-to-help-manage-chronic-fatigue-brought-on-by-covid-19. It's just a booklet on general chronic fatigue, and doesn't even mention ME, CFS...

Jeannette Burmeister has written a new thread after receiving a response to her complaint:

I was thinking about this just the other day. It seems the ME/CFS community is the only place where this is discussed and challenged. That's not good enough. Why is the rest of medicine/clinical science silent?

Could it have been the antibiotics (assuming these were administered concurrently) or even steroids, which it seems were given at that time? These improvements in ME/CFS after antibiotics seem to be documented quite frequently in the patient community.

The patient in this study is the first author. I'm not sure that it is good practice to do this without mentioning the fact.