Search results

An Australian paper. Authors: Chansavath Phetsouphanh 1*&, David Darley 2*, Anette Howe 1, C. Mee Ling Munier 1, Sheila K Patel 3, Jenifer A Juno 4, Louise M Burrell 3, Stephen J Kent 4,5, Gregory J Dore 1,2, Anthony D Kelleher 1,2†& and Gail Matthews 1,2†& The Kirby institute...

Are you perhaps thinking of the target training heart rate that Workwell suggest people with ME/CFS routinely keep their heart rate under, so as to avoid PEM? I don't think I've seen any good evidence yet for the idea that keeping your heart rate below a percentage, e.g. 60% of maximum heart...

Interesting paper from a couple of researchers from the Laboratory of Cellular Oncology, National Cancer Institute, NIH, Bethesda. I've copied the bits I found most interesting and understandable (which was not the methodology). It sounds like substantial advances are being made in techniques...

It's an interesting question as to whether 100% of people with ME/CFS show the drop in performance at VT. We don't know if a person with ME/CFS could show that drop in a paired CPET, but another week, perhaps when well rested, not show that drop. Or if some people need to do more than 8...

There's been a shift over time, away from 'people with CFS are all perfectionists' and even 'people with CFS all have perfectionist mothers' to 'people with CFS who are perfectionists are sicker and more depressed than those who aren't'. I guess that's a result of studies finding, despite the...

It could be, as in my case I think, that the researchers applied a significant amount of caution with people with ME/CFS and/or were happy when data supportive of their hypothesis was achieved, and stopped ME/CFS participants when they got to RER=1.1, rather than letting them continue on for a...

On that thread, @wdb mentions a study that had people with ME/CFS and controls do paired CPETS (Lien et al, 2019) Abnormal blood lactate accumulation during repeated exercise testing in myalgic encephalomyelitis/chronic fatigue syndrome The chart below is comparable to the ones from the Van...

For the female study, there were 24 people diagnosed with ME/CFS and classed as severe who somehow managed to do two CPETs, appropriately spaced. They were left out of the analysis due to them not being appropriately matched with the ICF, which is fair enough. Van Campen did a study...

Sure, I'm just not sure what RERs were reported in the studies- I haven't looked. @Snow Leopard mentioned about effort perhaps being less than full based on heart rates. Edit - the RERs look fine >=1.1 in both males and females, ME/CFS and ICF.

Yes, but look at the change in Vo2 at the ventilatory threshold in both males and females: Male Female The split looks suspiciously too perfect for the paired CPET to not be playing some part in the diagnosis decision. I mean, assuming the diagnosis was made before the CPET, what if an ICF...

Yaay, I'm so glad that you found that study @cassava7. So this is about children and young people reporting on treatment acceptability and whether their symptoms improved. It pretty much eliminates Crawley's modus operandi. Maybe Bergman will be good.

So, these are the reviewers (again). Consumers: Mary Dimmock (USA, carer, person with ME/CFS advocacy background), Kay Hallsworth (UK, person with ME/CFS); Clinicians: Todd Davenport (USA, physiotherapy), Julia Newton (UK, medical); Systematic reviewers with relevant methodological expertise...

Thanks @Sean, there's lots of good bits to quote in that article. e.g.

(Coincidentally, speaking of Glasziou and previous Cochrane Exercise Therapy Reviews and natural progressions) I was having a look at David Nunan, really wanting him to be a person I could have confidence in. Turns out we already have a thread on a paper that he has co-authored, here: Key...

From the description of the paper in google scholar: So, apparently Ugandan primary school children with poor reading skills were taught to apply key concepts - these ones: Treatments can harm.*† Anecdotes are unreliable evidence.*† Association is not the same as causation.† Common...

Oh, the irony. Here's the full list of authors: Iain Chalmers, Andrew D Oxman, Astrid Austvoll-Dahlgren, Selena Ryan-Vig, Sarah Pannell, Nelson Sewankambo, Daniel Semakula, Allen Nsangi, Loai Albarqouni, Paul Glasziou, Kamal Mahtani, David Nunan, Carl Heneghan, Douglas Badenoch I was looking...

It's not about being a diagnostic marker - it's to demonstrate that there is a real consequence from exercise, that it can make people very sick. And exercise every day has a cumulative effect. Still, many people do not believe that. If there are CPETs, there is data to accompany what people...

Fair enough, it certainly wouldn't be for everybody. But people are still talking about GET trials, and trials of CBT to convince people they need to increase their activity levels - and ethics boards are approving them. People are putting their health at risk every day already. If you got a...

I don't think we can know that from the information in the papers. They say the CPETS were done to assess exercise intolerance. It seems unlikely that the male study did not have a single person diagnosed with ME/CFS who did not show a drop in performance. That's a pretty impressive diagnosis...

I would do it, because if there is a constant decline during that period, it says a lot about how GET is damaging. And I don't want my son and all the other young people now and to come to have to live in a world where the BPS view about ME/CFS has credence. ...Well, maybe I'd do a week. And...