Search results

Yea usual crap (maybe not appropriate on the day that's in it) reminds me of @strategist and @Jonathan Edwards comments here* "system that allows even homeopathy to reach the status of evidence based treatment for almost any condition (if sufficiently subjective endpoints are chosen)". The...

Yea, I copy my emails to NICE, re the use of GRADE/Cochrane, to the LongCovidSOS group and the covid APPG i.e. as well as the ME/CFS APPG. I've also emailed the LongCovidSOS group to encouraged them to learn from the ME/CFS's communities experience [Note*]. I've also contacted Dr Nisreen Alwan...

@Jonathan Edwards highlighted the quality of the NICE team which produced the new ME/CFS guideline - but surely the system should be able to maintain standards. Reminds me of the 2007 ME/CFS guideline (to be clear I've never read it); which seemed to be the product of a particular team and an...

It's late and I don't keep up with this but I still have (unevidenced) opinions! Surely a draft NICE guideline would be published and consulted on i.e. before it is adopted - correct? I'd like to think that the Long covid charities would be aware of the risk of being fobbed off with unevidenced...

Family member(s) have been looking at this. Slight nuance, 28 days from the date symptoms first appeared --- i.e. rather than 28 days from a positive test ---- brought target vaccination date forward for my family member (UK).

I'm guessing that sampling is the biggest problem - it's pretty difficult to swab your tonsils (gag response) and I think you need to push the swab pretty far up your nostrils --- too much info!

Re private sector role, only scanned but this reminds me of Dido Harding of the disastrously (from the taxpayers point of view) track and trace. I wouldn't hold out much hope re getting NICE back to its original concept - producing evidence based guidelines. I'd expect more wheeling and dealing...

My daughter got covid about 1 month ago and she tested (LFT) positive two weeks after the infection. She checked online and NHS workers are told not to do LFT for 3 months after an infection - so LFTs seems to give false positives, after you've been infected, i.e. as well as false negatives...

Yea I vaguely recall a series of short (15 minute?) programs on Radio 4 and one looked at how you can manipulate people by showing empathy etc. and it was a cheap way of getting + ve feedback (questionnaires). So this might be the agenda - make it look like your doing something (media spin)...

Yea LFT is the abbreviation for lateral flow test and it misses positive infections (compared to a PCR - the gold standard test but still not 100%). Interesting that there seems to be a lag between being symptomatic and a positive LFT --- presumably PCR would be +ve in this lag period. Wonder...

I feel I should compliment the creative writing. Maybe Cochrane could try to live up to the mission statement rather than just saying it. Is P.R. Philippe Ravaud?

Monetising the asset? I mean to say, look at the value of what they have created!

Where to start --- 'fundraising income'? reminds me of the comment from a Doctor re the Royal College's taking in money to fund the wine cellar! Paul Garner's ain't cheap!

Been avoiding sending this reply to (Katy) NICE* --- finally got around to it. Thank you all for your comments etc. *"Katy, thank you for your response. Regarding your comment: "Each review question in the NICE guideline has its own review protocol agreed by the guideline committee. These...

There's a fairly old Hornig & Lipkin study which suggested changes in cytokines with duration of illness and Ron Davis presented some data (Montoya study?) at an OMF symposium. However, I think @Jonathan Edwards may not be convinced that the cytokine data really indicates much - I think I can...

Last I heard of the medicines was negative i.e. the UK bought a load of stuff that was effective in unvaccinated people --- but in vaccinated people (most of the UK population) it isn't effective. So £500 million down the drain? I'm not sure what to make of the drugs used to treat serious...

Yea the 1918 influenza pandemic was another influenza but it took a hell of a toll. I wonder if the models these guys are working from really have enough data --- the global transmission rates are so high this virus has the opportunity to check out a lot of combinations (variants). I am too; I...

Certainly and I've had mine --- I suppose I was thinking more generally i.e. that vaccines will cease to work due to new variants, rather than decreasing immunity (with time).

EDIT see @Trish comments below - I've had my booster and I pre-booked it to get the slot immediately I was eligible. OK this time it looks like a booster will (at a population level) work but generally I'm concerned that new variants will simply make a vaccine ineffective. New variants seem to...

Not actually answering your question, but I vaguely recall something recently (months) where scientists (Oxford?) found that whole genome sequencing found underlying mitochondrial disease [EDIT - apologies just re-read this - the symptoms were very variable and not actually consistent/typical]...