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  1. InitialConditions

    UK: All Party Parliamentary Group (APPG) on ME news, 2020 onward

    I didn't know that they outsourced it. This seems like the sort of work that could be done in-house, especially if your org has 25+ staff.
  2. InitialConditions

    UK: All Party Parliamentary Group (APPG) on ME news, 2020 onward

    Minutes for the 2023 AGM. The minutes for the regular meeting that followed the AGM will be published once they are approved at the June APPG meeting.
  3. InitialConditions

    Efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19: results of a randomized controlled trial 2023, Kuut, Knoop et al

    Standard deviation shows spread, but standard error is used to compare means between groups, usually via significance testing using confidence intervals. But in this case, as the numbers in the two arms are essentially the same, we can just use standard error as a proxy for standard deviation.
  4. InitialConditions

    FINE trial patient booklet 29/04/05 Pauline Powell

    Thanks, but I've got that one, @Dolphin, I'm looking for the Liverpool CFS service document mentioned in the previous few posts.
  5. InitialConditions

    FINE trial patient booklet 29/04/05 Pauline Powell

    Does anyone have a copy of this document? The above link won't let me download.
  6. InitialConditions

    United Kingdom: ME Research UK (MERUK) News

    ME Research Annual Report 2022 (published May 2023)
  7. InitialConditions

    Typing myalgic encephalomyelitis by infection at onset: A DecodeME study, 2023, Bretherick et al

    One of Sarah's main criticisms is on the purpose of the paper: What exactly is the take home message? What are the main results? I agree with her that this needs work. The paper is essentially an initial overview of the questionnaire respones and some 'association fishing', but people want clear...
  8. InitialConditions

    Typing myalgic encephalomyelitis by infection at onset: A DecodeME study, 2023, Bretherick et al

    I've just seen the first review, from Prof. Sarah Tyson, has been posted, and is a 'Not Approved'. There are some good points in there that I agree with, and some stuff I don't.
  9. InitialConditions

    Socioeconomic inequalities of Long COVID: a retrospective population-based cohort study in the United Kingdom 2023 Shabnam et al

    It's a sarcastic joke, based on the prevalent stereotype (at least in the late 80s/90s) of ME being an illness that afflicted only (or primarily) young professionals (yuppies), who were middle-class, socially mobile, with a well-paying job. So yes, I'm juxtaposing that stereotype with the result...
  10. InitialConditions

    Report: (ME/CFS) Services in Scotland: Findings from an analysis of surveys issued to NHS Boards in Autumn 2022

    There is some information on the current situation with Scotland and the NICE guideline, here: https://meassociation.org.uk/medical-matters/items/nice-guideline-northern-ireland-scotland-wales/
  11. InitialConditions

    Dr Karl Morten - UK researcher based at Oxford University

    I think he's saying (b), but I don't agree that's what we need.
  12. InitialConditions

    Dr Karl Morten - UK researcher based at Oxford University

    I have added some tweets to that thread. I don't agree that we need hypothesis-driven proposals (quite the opposite—we have too many dispararte hypotheses in ME/CFS research, IMO). I also would like to know how many proposals the Morten group have submitted to MRC.
  13. InitialConditions

    Efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19: results of a randomized controlled trial 2023, Kuut, Knoop et al

    Another possibility is that the means are estimated at T1 and T2 because the true means cannot be calculated due to dropouts (but they can be calculated at baseline). This is apparently what intention-to-treat analysis deals with.
  14. InitialConditions

    Efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19: results of a randomized controlled trial 2023, Kuut, Knoop et al

    This is the key part of the text explain the method to achieve the values in Table 3. It seems convoluted to me, and perhaps these numbers are 'modelled'. But, if this is the case, why not just use the actual values!
  15. InitialConditions

    Efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19: results of a randomized controlled trial 2023, Kuut, Knoop et al

    One question I have: the title says 'Estimated means and linear mixed model analyses....' What do they mean by this? Are they showing results from some extra modeling step? EDIT: And why are T1 and T2 means referred to as 'Estimated means', whereas the baseline value at T0 is just 'mean'...
  16. InitialConditions

    Efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19: results of a randomized controlled trial 2023, Kuut, Knoop et al

    If it's not too much trouble, @ME/CFS Skeptic, are you able to resend this image with the repeated SEs at T0 also highlighted. There is one instance. Cheers.
  17. InitialConditions

    Efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19: results of a randomized controlled trial 2023, Kuut, Knoop et al

    This is used to calculate the error on the between-group difference. The SE we have flagged are on individual groups (i.e., calculated before that stage), so this shouldn't matter.
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