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  1. Wyva

    Metaresearch on patient-reported outcomes in trial protocols and results publications suggested large outcome reporting bias, 2025, Heravi, Busse et

    Ala Taji Heravi ∙ Dmitry Gryaznov ∙ Jason W. Busse ∙ Christof Manuel Schönenberger ∙ Belinda von Niederhäuserne ∙ Lena Hausheer ∙ Manuela Covino ∙ Johannes M. Schwenke ∙ Selina Epp ∙ Alexandra Griessbach ∙ Malena Chiaborelli ∙ Arnav Agarwal ∙ Szimonetta Lohner ∙ Julian Hirt ∙ Stefan...
  2. Wyva

    Cardiovascular disease prevention and management in COVID-19: a clinical consensus statement of the European Association of (...), 2025, Vassiliou et

    Full title: Cardiovascular disease prevention and management in COVID-19: a clinical consensus statement of the European Association of Preventive Cardiology, the European Association of Cardiovascular Imaging, the Association of Cardiovascular Nursing & Allied Professions, the European...
  3. Wyva

    Upper respiratory tract immunization with Pam2Cys-adjuvanted spike protein vaccine achieves sterilizing protection against SARS-CoV-2, 2025, Stewart +

    Abstract Injected COVID-19 vaccines protect against severe disease, but do not induce robust mucosal immune responses. Nasal vaccines offer the advantage of local immunity to block viral infection and transmission. Previously we showed immunization of a Pam2Cys-adjuvanted SARS-CoV-2 vaccine to...
  4. Wyva

    What the epidemiology of glandular fever might tell us about ME/CFS

    About mono/glandular fever: it is the same in Hungary. I never heard of it until I got mono myself in my early thirties (leading to my ME/CFS). I don't remember any high school/college kids I knew who had it. Whenever I tell my story, I need to explain to people what mono is, they don't know...
  5. Wyva

    Age-Related Changes in the Clinical Picture of Long COVID, 2025, Fain, Hornig et al

    ABSTRACT Background This study evaluated the impact of aging on the frequency and prevalent symptoms of Long COVID, also termed post-acute sequelae of SARS-CoV-2, using a previously developed Long COVID research index (LCRI) of 41 self-reported symptoms in which those with 12 or more points...
  6. Wyva

    Early Growth Response Gene 1 Benefits Autoimmune Disease by Promoting Regulatory T Cell Differentiation as a Regulator of Foxp3, 2025, Yang et al

    Abstract Foxp3+ regulatory T (Treg) cells, as one of the subtypes of CD4+ T cells, are the crucial gatekeeper in the pathogenesis of self-antigen reactive diseases. In this context, we demonstrated that the selective ablation of early growth response gene 1 (Egr-1) in CD4+ T cells exacerbated...
  7. Wyva

    Problematic advocacy organisation in Czechia - "Neúnavní" (indefatigable)

    Yes, I've been following them on Facebook and I've been wondering about all this myself. (I think I even mentioned it here on S4ME that their sloth mascot was an interesting choice.) I don't speak Czech, so I can only judge their activity based on what I saw in the FB translated versions of...
  8. Wyva

    Review (Hungary) Interdisciplinary consensus statement about the diagnosis and treatment of [CFS]/myalgic encephalomyelopathy, 2025, Simonyi et al

    David Tuller was very kind to cover this story about how they misrepresented what the NICE guideline says on the Virology blog: https://virology.ws/2025/08/23/trial-by-error-hungarian-experts-make-goulash-out-of-nice-recommendations/ "Remarkably, the authors managed to mangle the core findings...
  9. Wyva

    Shingles vaccines, chickenpox, Shingrix

    You forgot to mention the drop bear :emoji_koala::skull::dizzy:
  10. Wyva

    “Have you considered that it could be burnout?”—psychologization and stigmatization of (...) long COVID or post-COVID-19 vaccination syndrome, 2025,

    Full title: “Have you considered that it could be burnout?”—psychologization and stigmatization of self-reported long COVID or post-COVID-19 vaccination syndrome Ronja Büchner, Christian Sander, Stephanie Schindler, Martin Walter, Carmen Scheibenbogen & Georg Schomerus Abstract Background...
  11. Wyva

    Improvement in Upper Limb and Systemic ME/CFS Symptoms After Surgical Treatment of Neurogenic Thoracic Outlet Syndrome, 2025, Christoforou, Rowe et al

    Full title: Improvement in Upper Limb and Systemic Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Symptoms After Surgical Treatment of Neurogenic Thoracic Outlet Syndrome Maritsa E. Christoforou • Ying Wei Lum • Sally C. Sroge • Alba M. Azola • Peter C. Rowe Abstract Thoracic...
  12. Wyva

    Scientific Reports is looking for submissions: Post-acute infection syndrome (PAIS)

    Submission status: Open Submission deadline: 13 May 2026 This Collection welcomes studies into improving diagnostics and tools to determine disease progression, pathways affected, and clinical interventions, both studies within and across infectious agents of PAIS. Q-fever, Lyme disease...
  13. Wyva

    Long COVID-19 alters muscle architecture and muscletendon force transmission: a one-year longitudinal study, 2025, Ferreira et al

    Leandro Ferreira, Isabella Da Silva Almeida, Rochelle Rocha Costa, Gabrielle Vieira Roriz, Jeam Marcel Geremia, Joao Luiz Quaglioti Durigan, Rita de Cássia Marqueti Introduction: There are limited studies on the long-term effects of COVID-19 on skeletal muscle morphology and architecture...
  14. Wyva

    Variability in Long COVID Definitions and Validation of Published Prevalence Rates, 2025, Wisk et al

    Key Points Question What is the prevalence of long COVID in the Innovative Support for Patients With SARS-CoV-2 Infections Registry (INSPIRE) cohort based on definitions in published literature? Findings In this prospective cohort study of 4575 INSPIRE participants, when replicating long...
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