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I don't think the frequency matters. A single dose can cause bleeding. The lowest dose I know of is 250mg, which is enough to be a problem.

I gave up using naproxen around 2000 because I came to realise that the risks of gut haemorrhage are pretty unacceptable. I would not take it myself now. The pharmacological effect is the same as ibuprofen. If I need a stronger effect I use a higher dose of ibuprofen.

I wouldn't use a private lab and I think finger prick tests are much much more likely to end up producing spurious abnormal results. I would have thought it was up to your GP to find an NHS solution.

The bitter truth is that you can fool some of the people all of the time and all of the people some of the time but not all of the people all of the time. Especially if you keep contradicting yourself.

My guess would be that the virus is not expelled from the nose except when sneezing. But if someone is infected they will almost certainly tough their nose and then wipe virus of the rails and seat handles.

I am not sure this is really irony. It is the same as before - telling people what they should do without evidence. Before we get people exercising" need "to be sure it’s going to be safe. We need proper evaluation of cardiac and respiratory function" &. "take things slowly and in a paced...

yes

The molecule seems to be just one Ig domain, being what is n=known as Vh (variable domain of heavy chain). That many well mean that it is small enough to be lost in urine so the half life may be quite short - a day or two maybe. IgG is around 20 days. A potential problem is that the specific...

The key issue is whether or not hypermobility has any causal association with either multiple soft tissue injuries (subluxations, sprains etc.), ME-style 'fatigue' problems (PEM, brain fog, POTS etc) or internal organ problems like gut issues. There is no doubt that some people with lax joints...

Piece in the Guardian today about LongCovid quoting Charles Shepherd. Nothing very new.

@Binkie4 But it isn't accepted as such by the medical community at large, only by a small group of 'experts' who devise criteria for 'hEDS' based on what they see in clinics. The great majority of my colleagues see this as 'not fit for purpose' but unfortunately professional bodies are not...

I think you have misunderstood me.These people you describe are clearly not normal. But I very much doubt that hypermobility is the cause of their problems. So each must have some other undiagnosed problem. For some that may be the same and others different but we do not know what the problems...

But you mentioned ankles, which is why I queried it. There is no such thing as partial dislocation generally speaking. There is something called subluxation but even that is pretty unlikely even in people with EDS except in shoulder and finger joints. Hip dislocation is a major event, not...

There is a bit in the on-line Guardian about this. Maybe you need to go to Aberdeen!

I don't have any idea of the logistic options. I guess the nursery have to say what they have been told should be done - if they have. I suspect the chances of a false negative are quite high whatever is done now so the two week isolation must be the right way forward anyway.

The term 'preprint' has a longstanding technical meaning - a paper that has passed peer review but is not out yet - i.e. a 'reprint' ahead of time. It seems to be used here for a manuscript. I don't mind people putting manuscripts on the net, I think it is a good idea. But it means that nobody...

Disappointing to see such a poorly organised abstract - I am not tempted to read the paper. It contains no study design and no data, simply musing conclusions. I am not a great fan of the peer review system but at leat once upon a time it filtered out stuff as uninformative as this.

No, they must have been improving anyway - in order to have done the exercises!

I think that is exactly the point David was making himself.

What I find so odd is that anyone should take R M-M seriously when she so obviously is unqualified to say anything meaningful, just by the way she talks about things. She talks just like a homeopath.