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  1. Sean

    News from the USA, United States of America

    Kennedy is so nothing more than proving beyond doubt all the deep concerns and fears people had about him before he got the job.
  2. Sean

    Mixed methods study of views and experience of non-hospitalised individuals with long COVID of using pacing interventions, 2024, McMullan et al

    There is absolutely no evidence that patients lack motivation. None. If by improving activity planning they mean increased opportunity to implement plans then that might be true, to some modest degree. But if they mean we get more skilled at planning, in the improved cognitive ability sense...
  3. Sean

    News from Aotearoa/New Zealand and the Pacific Islands

    Surprisingly good, particularly considering the other news often coming out of NZ on post-infection stuff.
  4. Sean

    Measuring the fitted filtration efficiency of cloth masks, medical masks and respirators, 2025, Tomkins et al.

    Masks sometimes come in two versions, one shaped for Asian faces, and another for everybody else. Might be worth checking that out.
  5. Sean

    Measuring the fitted filtration efficiency of cloth masks, medical masks and respirators, 2025, Tomkins et al.

    Quite extraordinary and disturbing, isn't it. So much suffering and death could have been prevented by a simple, cheap, safe, proven protection. Yet here we are. Somehow it has become thoroughly politicised and demonised, probably beyond repair any time soon.
  6. Sean

    Opinion What are the top replicated ME/CFS findings?

    This is an important factor in general to control for in ME/CFS research, not just for ESR. I suspect we are going to see two different overall profiles: one during the initial stages, then a change to a different profile after that. I would need to check, but IIRC I had a low ESR early on...
  7. Sean

    Protocol Impact of Tai Chi Therapy on Fatigue and Cognitive Function in Individuals With Chronic Fatigue Syndrome: Protocol for a Pilot... 2025 Wang et al

    Isometric exercises are excellent, for the rest of the population, but not for me any more. Pre-ME I used to score high in general fitness tests and exercise capacity. Suddenly I didn't and couldn't any more, at least not without sometimes extreme payback.
  8. Sean

    Review Impact of Exercise to Treat Postural Orthostatic Tachycardia Syndrome: A Systematic Review, 2025, Cortez et al

    Adding a comma makes a lot more sense. ...and can result in a worsening of a constellation of symptoms, leading to extreme fatigue, cognitive impairment and flu-like symptoms within hours or days after exertion, lasting days to weeks.
  9. Sean

    Protocol Impact of Tai Chi Therapy on Fatigue and Cognitive Function in Individuals With Chronic Fatigue Syndrome: Protocol for a Pilot... 2025 Wang et al

    Chronic fatigue syndrome (CFS) is a psychosomatic disorder characterized by persistent fatigue, primarily involving physical and mental exhaustion, with greater emphasis on the latter. So much wrong in so few words. That takes some skill.
  10. Sean

    Replicated blood-based biomarkers for Myalgic Encephalomyelitis not explicable by inactivity, 2024, Beentjes, Ponting et al

    Yes, the volume of a room is not determined by measuring its temperature.
  11. Sean

    E-readers (Kindle, etc.)

    Also worth checking Librivox, which is the audio book equivalent of the Gutenberg sites. (i.e. All public domain sources only, so tends to be older stuff.) It is an entirely volunteer project, so the quality of both the reading and recording is variable, but there is some good stuff on there and...
  12. Sean

    Brief Outpatient Rehabilitation Program for Post-COVID-19 Condition, Nerli et al, 2024 - with comment from T. Chalder

    What else does it imply? Clinically significant is a minimum threshold value. Why bother even defining such a value if you are going to then ignore it? Sorry, I forgot. Psycho-behavioural studies don't have to follow standards, not even their own.
  13. Sean

    Crowdfunding for David Tuller during April 2025

    Made the second of my two donations. :thumbsup:
  14. Sean

    Evidence-based medicine

    Not to mention being honest about it.
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