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  1. Adrian

    Coronavirus - worldwide spread and control

    I wonder if there is a real issue that there aren't any politicians with a scientific background and I suspect that they don't know how to analyze the data and ask the questions. So they end up not asking their scientific advisors who don't seem to know what they are doing and don't understand...
  2. Adrian

    Advice from 'experts' on post-viral fatigue following Covid-19 (NHS Oxford Health, Science Media Centre, ...)

    @PhysiosforME have published a response https://www.physiosforme.com/opposition-to-fatigue-leaflet Letter signed by various groups https://cec5c48f-2e98-4bb8-9110-208373420a79.filesusr.com/ugd/4f94c1_c7aa8bd5b9c748888a32e5e992dd323f.pdf
  3. Adrian

    Coronavirus - worldwide spread and control

    That doesn't surprise me I think quite a few older people isolated early on. I think the spread over different regions is a huge factor which may well dominate over any other factors. London has been bad and that (I guess) is the area where people are most likely to travel to work by train.
  4. Adrian

    UK - Resources for help getting food during quarantine and other supermarket related problems

    The guardian is starting to cover some of the issues https://www.theguardian.com/society/2020/apr/19/disabled-people-left-off-coronavirus-vulnerable-list-go-without-food
  5. Adrian

    Coronavirus - worldwide spread and control

    The UK figures quoted are hospital deaths so they are not the ONS figures which look at death certs. There are corrected hospital figures which correct for the day of death rather than the day that the report was made.
  6. Adrian

    Coronavirus - worldwide spread and control

    There is a report here on spread https://nextstrain.org/narratives/ncov/sit-rep/2020-04-17?f_country=USA They let you see the data and do your own analysis by the looks of it. They have a player that plays through the spread patterns https://nextstrain.org/ncov/north-america/2020-04-17
  7. Adrian

    Coronavirus - worldwide spread and control

    I believe the New York cases came from Europe - there was an article around tracking of mutations that suggested this.
  8. Adrian

    Coronavirus - worldwide spread and control

    If you look at the UK the major city (London) was hit early and in a big way - and London is around 13% of the UK popuation. I wonder if the US population is more spread. In the US New York was hit but other large cities (such as Houston) weren't but still locked down (relatively early). So...
  9. Adrian

    Coronavirus - worldwide spread and control

    This document shows some potentially interesting correlations over different areas in the UK with infection numbers against various stats such as population density, age, disability, deprivation etc I'm not sure what to make of any of them in terms that none look that great a correlation to me...
  10. Adrian

    Coronavirus - worldwide spread and control

    My suspicion is that they don't have the data collected. One of the things I've been shocked about is the poor quality of data available it it taking a long time for reports to get through. But it does make me wonder if they don't have the data how can they make proper decisions. They are...
  11. Adrian

    Patient experiences and the psychosocial benefits of group aquatic exercise to reduce symptoms of ME/CFS: a pilot study, 2020, Broadbent et al

    Isn't there a wider point here in that you can't do a meta analysis over the effectiveness of an intervention by including multiple different interventions. If Cochrane wants to review GET they need to go back to the treatment protocols and classify what is actually meant by GET. If they want to...
  12. Adrian

    The biology of coronavirus COVID-19 - including research and treatments

    I thought one of the interesting things he talked about was whether the bad symptoms (putting people in ICU) were due to the virus or I think he was suggesting that they were due to the host response to the virus.
  13. Adrian

    The biology of coronavirus COVID-19 - including research and treatments

    I'm confused about what is happening with Vaccines. There is the Oxford group https://www.theguardian.com/society/2020/apr/18/coronavirus-vaccine-trials-could-be-completed-by-mid-august who are claiming that they will have a vaccine tested by September. Yet others (including Lipkin) talked about...
  14. Adrian

    Coronavirus - worldwide spread and control

    As I understand it Apple and Google aren't supportive of the NHS app which presents problems in that for it to work the phone needs to be unlocked and the app needs to be in the forground. They are doing their own library to support apps that have a decentralized privacy model instead but the...
  15. Adrian

    The biology of coronavirus COVID-19 - including research and treatments

    From the presentation they did at the CMRC conference it seems like a very good facility with quite automated testing at good scale.
  16. Adrian

    Advice on mask-wearing to protect against Covid-19

    This looks like a good article on the advantages of wearing masks and how it affects R0. It goes through the different bits of evidence. https://www.fast.ai/2020/04/13/masks-summary/
  17. Adrian

    The biology of coronavirus COVID-19 - including research and treatments

    This paper came out yesterday talking about ACE-2 receptors and the relationship with SARS. https://www.biorxiv.org/content/10.1101/2020.04.10.036418v1 Also another story talking of ACE2 receptors...
  18. Adrian

    Coronavirus - worldwide spread and control

    Not sure. Hancock talked about it today so it could happen sometime in the next 10 years. The concern would be what data they are tracking. They talked about releasing source code but they also need to publish protocols they are using for review.
  19. Adrian

    Coronavirus - worldwide spread and control

    The point about what the DP-3T group are trying to do is to reduce the privacy risks by not having central data collection. If you don't have good data then it is hard to abuse the privacy of individuals - although correlation with mobile records could be possible. I did see something...
  20. Adrian

    Coronavirus - worldwide spread and control

    I thought is was a great cartoon. I've not read through the protocols yet but I suspect there is some complex maths behind bits of it and cryptography is often not easy to explain or understand.
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