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It appears that most people will get better regardless of what they do or don't do. A controlled study is needed to distinguish the effect of treatment from the effect of time passing.

Hey at least we're a threat now. That's better than being irrelevant and ignored. I hope I live long enough to see the functional disorder paradigm discredited entirely and exposed as mass delusion.

Things will never be as bad again as they were while the psychiatrists with their ideas were in charge. That experiment is over. ME/CFS is getting a lot more respect now on social media. More funding and research interest should follow.

In particular antibodies to interferon 1.

No one is surprised: In a way, it's an admission that they can't or won't do better clinical trials.

sC5b9 plasma levels are elevated in children with SARS-CoV-2 infection, even if they have minimal symptoms of COVID-19. A high proportion of children with SARS-CoV-2 infection met clinical criteria for TMA...

Does it make physiological sense to try and explain PEM as an inflammatory reaction of the brain, resulting from translocation of things into the brain that shouldn't be there, in turn resulting from problems with the blood-brain barrier?

Would cellular adhesion abnormalities influence gut and brain barrier permeability? There was this study which found an increase of gut bacterial translocation following exercise in ME/CFS.

Can you explain what role cellular adhesion play in the body and what kind of illness would result from its disturbance? Does it has anything to do with the endothelium?

https://www.nbcnews.com/news/all/havana-syndrome-likely-caused-microwave-energy-government-study-finds-n1250094

In these psychological narratives, the illness is always something that can be easily overcome. You just have to get over your own fears, face your sadness, release your true desires and so on. The pieces you need to solve the problem are all there, in your mind and just have to be rearranged...

I'm interested in understanding how they think.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703497/

The rhetoric against dualism and biological reductionism also rings hollow when what they practice is psycho-reductionism.

I can see how a therapist could do a lot of damage to patients by convincing them that the cause of their illness was that they were negating their true desires... with the therapist then explaing what these true desires were.

Yes, I enjoyed my life before I got ill. And now that I'm ill, the inability to do meaningful work in life is felt as large loss. So much for negating my true desires. I'm guessing the author confused the early signs of illness in patients, which made work hard and frustrating, with an...

The illness model proposed is one of mind-body divide, where patients negate their true desire to work less, and so that desire manifests in fatigue that forces patients to work less. Or something like that.

I read some of it. There are many accusations against society and patients for not believing in weird ideas with zero evidence behind them which illustrates well why patients want nothing to do with this kind of psychiatry (which is one of the accusations). Another reason is that these idas...

:sick:

It's by definition illness without any measurable abnormalities, but we're told the pathophysiology is known. That makes no sense.