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None of these findings are a smoking gun (and there are few questionable statements in the review), but it does suggest a particular hypothesis should be ruled out... This mention of kinesiophobia is total nonsense as these are patients who agreed to participate in a maximal CPET study. There...

This does give me some pause for thought. But peak power doesn't necessarily happen at the same time as VO2Peak. The graph shows there was in fact a drop in most patients, but that some controls also had a drop. A percentage drop would also be more relevant than just watts, but I'm not sure how...

@Simon M Regarding the VO2Peak and peak power findings, it is notable that patients exercised to a higher heart rate and slightly higher RER on the second day, compared to the first, whereas the controls were the reverse. This suggests that the encouragement worked well for patients, but not...

:emoji_face_palm::emoji_face_palm::emoji_face_palm:

Hong Kong has long had high-pressure work life (that could lead to those symptoms you mentioned), that is one of the reasons for Hong Kong's economic success compared to the rest of Asia. But Qigong itself is somewhat political, at least in mainland China. I'm not going to say more, due to...

See also: https://www.civillitigationbrief.com/2019/10/13/why-would-anyone-want-to-record-their-meeting-with-an-expert-witness-two-examples-where-the-courts-found-that-an-experts-statement-of-an-interview-was-unreliable/

x100000000000000

Well the choice of the statistical test is mutually exclusive, but it could be stated in the figure description. The frustrating part for me is the mean results and SDs were not provided (where the data was not skewed), along with a few other bits and bobs like the log10 tests, and respiratory...

The method used was paired t-test, which would compare the performance of the same participant on both days. If there is a consistent trend for most/all participants between both days then the p-value can indeed be that low. The test that was not used was the two-sample t-test which simply...

Sometimes scientists forget why scientific progress demands specificity...

It just takes some practise, you'll become a professional data torturer in no time!

Wow, incompetent assumptions know no bounds! Glad to hear they've finally admitted they're wrong though.

¯\_(ツ)_/¯ (caption - a giant shrug emoticon)

Wouldn't a SMD of 0.44 be a difference of slightly less than 2.3 points on the Chalder Scale? Thanks, Cochrane blocks VPNs and Sci-hub just links to Cochrane.

The classification itself is here: https://apps.who.int/iris/bitstream/handle/10665/43737/9789241547321_eng.pdf;jsessionid=E4FA0628374DF933232845E31A2204EB?sequence=1 It assumes a specific Model of Functioning and Disability (page 17) The key point is identifying the true limiting factor...

The problem is that this cannot be easily achieved in a dietary manner without starving yourself. Eating less sugar won't make much difference.

None of that bypasses the inherent bias of candidate gene association studies. These studies almost never replicate. https://www.biologicalpsychiatryjournal.com/article/S0006-3223(06)01470-3/fulltext

I bet it won't turn out that every patient has the mutation.

Authors seem to be confusing reported symptoms with "symptoms"...

What about positive bias in abstracts of systematic reviews? ;)