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  1. Hutan

    Trial Report Outpatient treatment of Covid-19 and the development of Long Covid..., 2023, Bramante et al

    New abstract Abstract Background: Post-acute sequelae of COVID, termed “Long COVID”, is an emerging chronic illness potentially affecting ~10% of those with COVID-19. We sought to determine if outpatient treatment with metformin, ivermectin, or fluvoxamine could prevent Long COVID. Methods...
  2. Hutan

    myHSN NHS Health Service Navigator website: What are examples of MUPS (medically unexplained physical symptoms)?

    Nope, I'm utterly confused. They seem to be suggesting that some people have MUPS that don't fit into a syndrome (I'll call this group 'non-syndromic MUPS'). And some people have MUPS that are part of an as-yet poorly understood syndrome e.g. CFS ('syndromic MUPS'). They talk about a group...
  3. Hutan

    Preprint: Treatment of Long COVID symptoms with triple anticoagulant therapy 2023 Laubshder, Pretorius et al

    I'm still not understanding. I still believe that trials with a sound set-up (RCT) can help us know what is going on. The real problem is that we have seen so very few good ones in ME/CFS. I haven't written off the idea of microclots. But I need to see some more solid evidence before I...
  4. Hutan

    Preprint: Treatment of Long COVID symptoms with triple anticoagulant therapy 2023 Laubshder, Pretorius et al

    This wasn't really research though, I'm not sure why you are defending it @rvallee. They had 90 patients who were already there, really wanting the treatment to work, they were treated and then they were asked how they felt. It's very much along the lines of a BPS study. They could have at...
  5. Hutan

    Havana Syndrome: U.S. and Canadian diplomats targeted with possible weapon causing brain injury and neurological symptoms

    https://afsa.org/havana-syndrome-there-was-moscow-signal An interesting read from an ex-Moscow embassy American diplomat, talking about the use of microwaves by Russians against the American embassy during the Cold War. I don't know, but what if giving the game away, in a deniable fashion was...
  6. Hutan

    Endothelial dysfunction in ME/CFS patients, 2023, Sandvik, Mella, Fluge et al

    That's a good point. But, there is the example of rickettsias. There is an Australian study that found a high level of latent rickettsial infection in people with ME/CFS symptoms. (I also have tested positive to rickettsias.) Brill-Zinsser disease does occur occasionally, as a reactivation of...
  7. Hutan

    Untargeted analysis in post-COVID-19 patients reveals dysregulated lipid pathways two years after recovery 2023 López-Hernández et al

    Paired analysis They had 13 patients with blood samples from their acute illness phase (3 mild; 8 severely ill; 2 critically ill with intubation) and then two years later, when they had persistent symptoms. They found 170 differences, but I think the differences are impossible to interpret in...
  8. Hutan

    Untargeted analysis in post-COVID-19 patients reveals dysregulated lipid pathways two years after recovery 2023 López-Hernández et al

    Mexican study - the authors are in no doubt that Long Covid exists and is important. It's not super clear from the abstract, but they have plasma samples from acute Covid-19 (28 people; mild, severe, critically ill) and negative Covid (15 people). The "post-Covid-19" group consists of 22...
  9. Hutan

    Facioscapulohumeral Dystrophy (FSHD)

    My son and I have sent samples off to the lab. The testing is free, and part of investigations into the genetics of neuromuscular disorders. I was interested to see that the scope of the investigations seems to be a bit wider than FSHD. I can't really see a down-side to doing this...
  10. Hutan

    Cushing’s Disease Presenting with Functional Neurological (Conversion) Disorder 2023 Ashrafzadeh et al

    Thinking about this over breakfast, I feel infuriated at the failure of the health system to care for this person. @Arnie Pye described what happened really well. Well, fair enough, a diagnosis of Cushings might missed for a while if the patient just has non-specific psychiatric symptoms and...
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