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Amazing Perhaps the researchers have divided their fibromyalgia population according to how good the patients are at drawing. Probably as good a subsetting as most others suggested for fibromyalgia. Interoception continues to be a confused but unproductive area of investigation. But still...

No controls... not healthy controls nor disease controls.

So, an acknowledgement that the usual "treatments" haven't really been shown to work. The solution - divide the population into subsets so that the right treatment can be provided to each group. Looking for subsets in a sample of 28 people? That's bad enough. Dividing them up according to...

Neil Riley manages to add another ME/CFS myth into his non-apology: There's the suggestion that people with ME/CFS are the Type A's, "driven people", with the implicit suggestion that it is our personalities that have contributed to us being sick. (As well as creating an unnecessary...

It isn't clear to me how someone who had one or more persistent symptoms prior to the Covid-19 infection would have been dealt with in this study. I don't see anything about excluding them, or asking for only persistent symptoms that are new.

So, the study can't answer the question of whether previous infections alter the risk of persistent symptoms.

Just an unfortunate pairing of words I think on the HEROES-RECOVER issue - two separate cohorts.

This post [link] has a comment about a conference presentation by Partinen and a link to the conference report. He seems to have some odd ideas, including that there is an ME personality.

It's certainly interesting and raises many questions for me. Was there some biased selection of the participants? How common is a finding of SFN in people who would rate themselves as healthy? How many of the people in the Type 3 group would meet ME/CFS diagnostic criteria? SFN has been raised...

The correspondence is from Nuno Sepúlveda and Francisco Westermeier. The criticisms seem fair. Excerpt: We then re-assessed the 13 studies selected by the PASC-ME/CFS study for the meta- analysis stage but now under the scope of the EUROMENE research protocol (Table 1). We found that all of...

"Sub-groups" have sometimes been used as a convenient "get out of jail free" card by researchers who couldn't find clear signals in their data taken as a whole, but who could find signals (often still in the realms of wishful thinking) if they sliced their (often already small) samples into...

Here's the full tweet from Donald Trump: My favourite reply is * an uncrustable being some sort of junk food pie

That is a substantially lower participation in the workforce than I have seen suggested before. So, two years after diagnosis, 50% had no wages income, and only 5.7% were earning an income that the authors suggest is roughly indicative of a full-time income.

Just a little quibble - there seems to be a suggestion, especially in the summary article, that the services and interventions have worked for a small number of patients. We don't have any evidence of that - improvements could have been the result of cold-water bathing or stomach massage or...

I'm looking forward to reading this paper. I agree with others that this is a really interesting approach (also agree with the gender gap comment :(). I wonder how many countries would have similarly strong and linked databases of medical records and income information available to...

I suspect that there might have been some bias in the demographics of the studies. I think it is less likely that the frail elderly and the very sick (people with high blood pressure that is rather resistant to improvement created by exercise) would have been signing up to do planking and wall...

This is an interesting paper, especially with the corroboration of the reduced ETS1 finding. Google AI said: The transcription factor Ets1 is is highly expressed in B cells, particularly in naive B cells, and plays a key role in regulating B cell development and function: Expression Ets1...

I doubt that it was the primary outcome scale that was the major problem here, causing the people who own the BC-007 intellectual property to pack up and go home. If patients were reporting miraculous recoveries in everything except fatigue, I'm sure they would tweak their experimental design...