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  1. Hutan

    Long COVID: sustained and multiplied disadvantage, 2022, de Leeuw et al

    This brief commentary is light on detail. It does note that the impact of Long Covid will be very different in affluent communities versus those communities that don't have easy access to quality health care, intergenerational wealth and affordable housing. Specifically, it mentions indigenous...
  2. Hutan

    Long Covid at the crossroads: Comparisons and lessons from the treatment of patients with ... (ME/CFS), 2022, Hunt et al

    I think this is a clearly written paper. Its argument and ideas aren't new to members of the forum, but it's useful to have them in a paper that can be cited. It concludes: Certainly it is true that the large numbers of people suddenly developing Long Covid, many of whom are medical...
  3. Hutan

    UK: NIHR funding opportunity: 22/37 Non-pharmacological interventions for fatigue management in adults with long-term health conditions

    I've received a copy of the 10 page Commissioning Brief - Background Information, attached here (there does not seem to be any constraint on posting it). A. It includes summaries of a number of studies on various specific health conditions e.g. ME/CFS and indeed anything that usually...
  4. Hutan

    Malingering and illness deception (2003) Halligan, Bass, Oakley

    I loved the tag that @Haveyoutriedyoga applied to this thread. I'll probably add a few more tags, but I thought it was worth immortalising in its succinct glory: Section 2, item 4 also had me snorting out loud.
  5. Hutan

    UK: NIHR funding opportunity: 22/37 Non-pharmacological interventions for fatigue management in adults with long-term health conditions

    Excuse my skepticism, but this looks like the psychosomatic gravy train rolling on. In fact, it's probably more like a steam roller, with the NICE ME/CFS guideline, the Long Covid guideline and others sitting like cupcakes on the road ahead: The deadline for submission of a proposal is...
  6. Hutan

    UK: NIHR funding opportunity: 22/37 Non-pharmacological interventions for fatigue management in adults with long-term health conditions

    Oh, they know that they work already, it's just a question of how much further they can be applied. (and how they might be tweaked to be more effective)
  7. Hutan

    Fine mapping of the major histocompatibility complex (MHC) in (ME/CFS) suggests involvement of both HLA class I and class II loci, 2021, Hajdarevic

    A warm welcome to the forum @Riad_Hajdarevic. Thanks for the interesting work you and the team there are doing. The forum thread for the new paper is here: Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci...
  8. Hutan

    Open UK - Recruiting: Novel Dynamic Proteomics Approaches to Investigate the Systems Level Pathology of ME/CFS

    Just further on that, I have seen some studies budget to spend tens of thousands of dollars on specialist participant recruitment firms (even while noting that most recruits will come via communication with patient organisations) but offer compensation of up to only a few tens of dollars in...
  9. Hutan

    Open UK - Recruiting: Novel Dynamic Proteomics Approaches to Investigate the Systems Level Pathology of ME/CFS

    There are some studies taking the bad day/good day approach. E.g. Chris Armstrong in Melbourne is doing one I think. That is a good approach, side stepping the issues with provocation studies. I think what these particular researchers are doing is mostly ok though. My questions are in line...
  10. Hutan

    Implementation statement in support of ME/CFS diagnosis and management, NICE, draft published for consultation

    Two posts discussing the response to the Implementation Statement (due 24 March) have been edited or deleted, pending S4ME committee finalisation of the approach.
  11. Hutan

    UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion

    Discussion of responses to NICE's Implementation Statement have been moved to Implementation statement in support of ME/CFS diagnosis and management, NICE, draft published for consultation
  12. Hutan

    Comparative Analysis of Extracellular Vesicles in Patients with Severe and Mild MECFS, Bonilla et al, 2022

    Just a shout out to the authors for a good description of ME/CFS in an abstract: I thought this was a decently written paper. The scattergrams don't suggest there is much to see here - see the CD19 and CD41a charts. I mean, I would be happy for this team to get funding to look at the EVs of a...
  13. Hutan

    Comparative Analysis of Extracellular Vesicles in Patients with Severe and Mild MECFS, Bonilla et al, 2022

    Yeah, this look at EVs would be great done as a longitudinal study - comparing bad day(PEM)/good day samples.
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