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There is no evidence for the app itself, which has not been tested in any clinical trials. The reference list are a few narrative reviews on "mind-body therapies" and the "biopsychosocial approach", along a few clinical trials with quite varied "mind-body" therapy approaches for conditions like...

Positive predictive values were poor, mean years - sensitivity - PPV (manually calculated by me for all you Bayes lovers) 9.7 - 11.5% - 6.3% 10.6 - 13.3% - 3.5% 11.7 - 9.84% - 5.0% 12.8 - 18.6% - 4.1% 13.2 - 16.7% - 6.8% 13.8 - 35.2% - 4.4% (curious loss of specificity, with a gain of...

More recently than May 2016, which is the only version on the Wayback Machine and did not have any references to such research. The notable part is they only care about difficulties answering the questions, not whether patients believe the questionnaire is relevant to their illness.

The problem is that there is a common bias, namely questionnaire answering behaviour. This method does not separate the effect of (a negative bias on) questionnaire answering behaviour from depression itself. The only way to resolve this is to use objective measures of fatigue on functioning.

The difficult part is establishing the relationship between cause and effect. Certain underlying risk factors may predispose for the outcomes above as well as doctors prescribing behaviour...

That is a bold claim... Sigh. It is not the lack of literal meaning that is the problem, it is the lack of meaningful application. There is no parallel to executing software on a body.

Brains are not arrays of digital logic gates with a fixed network configuration. Nerves themselves can die or regenerate, it is not merely the 'switching' (nerve firing) that is important. Epilepsy causes structural changes, so I'm not sure the analogy holds there. (note: a seizure is a...

Unless they provide a histogram, and account for participation biases... There may still be a lack of sample size to make any conclusions about an earlier age peak too.

Copied post Unless they provide a histogram, and account for participation biases... There may still be a lack of sample size to make any conclusions about an earlier age peak too.

I can't help but chuckle at the word "stressology". The problem with stress is the more people who use the word in ever increasing range of contexts, the less specific the meaning seems to be and the less useful the word is as a result. Despite the fact that he has tried to test this...

I need to clarify that the age doesn't really tell us much. The average age at enrolment in the study was 44.9, and the study only went for 2.4 years so this study can't really capture what happens at other ages.

I made a mistake, the lifetime prevalence didn't report sex, 57% was the overall sample. However 56% of the new cases were women.

It's not working for us at all. Are you able to download the full PDF?

Because people sat down and wrote "software", which ultimately a list of binary logic instructions telling a digital computer what to do in a linear manner. Formal languages (including programming languages) are very different from our thoughts, or biological signalling networks. Life is a...

www dot curablehealth.com/podcast/fiona-recovery-story-chronic-fatigue-syndrome I haven't listened to the interview and there is no transcript, so I have only read what was written. From a first glance, it is notable that there is no discussion of whether she is in remission and what she has...

Moderator note: A series of posts has been split from the thread 'Protocol - Persistent symptoms Reduction Intervention - A system change and evaluation PRINCE, 2015 onwards, Chalder Moss-Morris et al' ****** The software/hardware analogy is indeed nonsense and it invokes the same mind-body...

The impact on the satisfaction of human needs in ME & CFS is often worse than the comparison illnesses, hence a deeper examination is needed before forming any conclusions about the degree of causation and 'expected' impact.

Another 2.4 year prospective study. (mean baseline age of entire population was 44.9, 57% women) https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3427300 New onset 0.08%/year, mean age of 48.0. 56% of new cases were women. "Lifetime diagnosis at baseline" was 1.3%. (note this was...

Copied post Another 2.4 year prospective study. (mean baseline age of entire population was 44.9, 57% women) https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3427300 New onset 0.08%/year, mean age of 48.0. 56% of new cases were women. "Lifetime diagnosis at baseline" was 1.3%. (note this...

The study is somewhat superficial in it's exploration of prognostic variables and it is possible the prognostic variables shared between IBS and FM may reflect diagnostic biases. The authors also state "We had no measure of sexual abuse which has been mentioned in previous reports as a...