Search results

Neither. Biology is a process. You can't put human DNA in a test tube with all the essential nutrients for life and grow a baby.

First of all, we're talking about subsets of patients, secondly, physicians have long had selective vision and focused on the symptoms they want to see to validate their view of a particular disease. Patients play along by hitting the right notes (agreeing with the right words) so that they can...

Validated against what? They didn't ask patients whether they thought the questions made sense or whether they represented their illness experience. They didn't validate against any objective measures of functioning. Their "validity" is based on self-reference (similar bias applying to all the...

There is no scientifically demonstrated "placebo effect" besides transient pain reduction due to conditioning of the "endorphin" system. Everything else is regression to the mean (inevitable natural healing) or reporting biases. Undergoing very expensive, risky surgery very much is a major...

My worries are that lots of people with ME or CFS will worry they have CCI or worse, get misdiagnosed with it, get surgery and not have any sort of remission. Conversely, I also worry about the exclusionary aspect e.g. those people had a real disease, but the illness suffered by people with a...

The study also stated the (oversimplified and partially misleading, but common) assumption that: and I think it it's a waste of time trying to associate HRV measures with self-report measures since the biggest predictor of altered (reduced) HRV (compared to average population controls) is...

The "fatiguing" test was conducted on the adductor pollicis (one of the thumb muscles), but this doesn't exactly put much strain on the cardiovascular system (though a blood pressure cuff was used during some of the tests). The result shows that the nerve function itself is probably normal and...

There was money promised for endometriosis research over a year ago and yet there is still no plan on how that is going to be spent. https://www.theguardian.com/commentisfree/2019/mar/28/greg-hunt-pledged-25m-for-endometriosis-research-were-yet-to-see-a-cent We cannot assume anything.

The abstract reads like a cherry-picked narrative. I don't trust this narrative either, unless the individual in question agreed it was true. The likely reality is there was a lot of medical malpractice and the patient is still severely ill. Terry Segall, one of the authors also wrote this in...

I don't experience that pattern at all, makes me wonder if I have a different illness. For me, physical activity can increase brain fog, but prolonged cognitive activity doesn't make my legs any weaker.

Here are some more Jon Stone doozies: "Trick or treat? Showing patients with functional (psychogenic) motor symptoms their physical signs." https://www.ncbi.nlm.nih.gov/pubmed/22764261 followup: https://n.neurology.org/content/80/9/869.1.long "From psychogenic movement disorder to functional...

Reminds me of this speculative paper: https://spqr.eecs.umich.edu/papers/YanFuXu-Cuba-CSE-TR-001-18.pdf Claims it may be consequences of some sort of elaborate eavesdropping device. I'm not sure how credible that is though...

This is their latest review (Jon Stone and friends) (I guess no one informed them about how inappropriate their analogy is): Structural alterations in functional neurological disorder and related conditions: a software and hardware problem)...

There were a few gene expression studies published by her from 2003-2009ish, I'm not sure what is being referred to apart from that. (she left the CDC in 2007) You can have a look here: https://www.researchgate.net/profile/Suzanne_Vernon/publications

Blinding might be difficult, I mean it is obvious when you've been randomised to the crap carrot cake group. Blasphemy!

I think the cake went over my head on this one.

The forgot to mention the bit where you have to believe in pseudoscientific nonsense.

It's notable that the discussion about Jason Lindsley is well, somewhat different to what was presented in the article.. https://lancasteronline.com/news/local/battling-a-baffling-illness-jason-lindsley-finds-focus-calm-on/article_92334e98-a6e7-11e6-aaf5-c3f4a7a463d1.html

The "Time to achieve required numbers of cases" in longitudinal population based cohorts is interesting (Figure 3). The consequence that it takes decades, given an initial sample size of 500,000 to accumulate enough cases for common diseases.

Are you saying the cake is a lie!?!