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We've a number of threads about Hyland and his nonsense already including A test of the adaptive network explanation of functional disorders using a machine learning analysis of symptoms, 2018, Melidis, Hyland et al The extra‐pulmonary symptoms of severe asthma and the polysymptomatic...

Thread for paper here, Predictors of New Onsets of Irritable Bowel Syndrome, Chronic Fatigue Syndrome and Fibromyalgia: The Lifelines Study, 2019, Monden et al

I wonder what NICE guideline they would claim to be following with this.

Ref 10 is to this study, Evaluating soreness symptoms of fibromyalgia: Establishment and validation of the Revised Fibromyalgia Impact Questionnaire with Integration of Soreness Assessment, https://pubmed.ncbi.nlm.nih.gov/31711726/, which makes no mention of post-exertional malaise. Ref 11 is...

Abstract Objectives: Central sensitivity syndrome disorders such as fibromyalgia, provoke continued debate, highlighting diagnostic and therapeutic uncertainty. The Hyland model provides a way of understanding and treating the medically unexplained symptoms of central sensitivity syndromes...

Absolutely no mention of ME/CFS in the whole document, however they do note which references this single study, Fibromyalgia: a new facet of the post-COVID-19 syndrome spectrum? Results from a web-based survey, 2021, Ursini et al

Abstract Previous efforts to estimate the burden of fatigue-related symptoms due to long COVID have a very high threshold for inclusion of cases, relative to the proposed definition from the World Health Organization. In practice this means that milder cases, that may be occurring very...

Full title: Unified Protocol for the transdiagnostic treatment of emotional disorders in people with post COVID-19 condition: study protocol for a multiple baseline n-of-1 trial Background: Post COVID-19 syndrome, defined as the persistence of COVID-19 symptoms beyond 3 months, is associated...

$6,898 raised, 10% of target, 26 days left https://crowdfund.berkeley.edu/project/40018

Reference given for that last claim is from Rosmalen's Lifelines study.

Abstract Background Growing evidence suggests that in addition to pathophysiological, there are psychological risk factors involved in the development of Long COVID. Illness-related anxiety and dysfunctional symptom expectations seem to contribute to symptom persistence. Aims With regard to...

Trial By Error: Letter on Inflated FND Prevalence Rates Accepted for Publication https://virology.ws/2023/11/02/trial-by-error-letter-on-inflated-fnd-prevalence-rates-accepted-for-publication/

$4,797 raised, 7% of target, 28 days left https://crowdfund.berkeley.edu/project/40018

NIH Director's Blog. How Double-Stranded RNA Protects the Brain Against Infection While Making Damaging Neuroinflammation More Likely "When you get a run-of-the-mill viral infection, after a few days of symptoms your immune system typically fends off the bug, and you’ll make a full recovery...

Editor’s summary The central nervous system relies on pattern recognition receptors (PRRs) to trigger innate immune responses against neurotropic viruses, but excessive PRR activation can also contribute to neurodegenerative diseases. Dorrity et al. found that human neurons express particularly...

9,231 signatures at time of posting. https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review

Thanks for checking. No, there is no upper limit; if I remember correctly we have at least one participant in their 90s.

Row over ultra-processed foods panel highlights conflicts of interest issue at heart of UK science reporting https://www.bmj.com/content/383/bmj.p2514.full?ijkey=kUPwDIWXKvwww&keytype=ref&siteid=bmjjournals

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