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Here's our CoQ10 discussion thread CoQ10 - Coenzyme Q10 You can find more studies of CoQ10 by clicking on the tag top left. e.g. this one of post-Covid symptoms, click on the arrow in the quote title to follow the link

No placebo control, so it doesn't tell us much with any certainty. It's an observational study, which is okay, but the authors certainly should not be making statements like this: There is no way that they can know that the various mostly common ailments reported had anything to do with CoQ10.

I think it's easy to make an argument that the environment that government and health authorities create does affect how easy or how impossible it is for people to comply with the recommendations. People can be being told that they need to eat healthier and exercise more, while sugary...

Yeah. I've had this standard reply to my email this morning from a Cochrane officer who I know personally:

Just noting this from the 2019 (and of course the 2024) version So, most recent included study was in 2011.

Physio meets science but can't understand what it says

We have amended the title of this thread, and added a link in the first post of the thread to the beginning of the discussion about the 2024 relabelling

On Kennedy, from the article linked in the above post

Some discussion of this latest turn here also: Cochrane Review: 'Exercise therapy for chronic fatigue syndrome', Larun et al. - New version October 2019

Just noting the timing of this announcement, days before Christmas. I doubt that was chance. It's like how governments drop bad news on a Friday, knowing that the journalists won't be working for two days, and hoping that by Monday everyone's attention will be on the next thing.

Wow e.g. Caroline Struthers has replied

That's an excellent comment. I would go further and suggest that many of the criticisms apply more widely to literature on all sorts of behavioural interventions for all sorts of medical conditions. A careful consideration by Cochrane of the risk of bias in unblinded trials of interventions...

I've changed the title of the petition to Cochrane: Withdraw the harmful 2019/2024 Exercise therapy for CFS review for now. We probably need to add an update as an edit to the 'Why this petition matters', and we'll get another petition update out before Christmas.

I had previously commented that a 2019 review was becoming more irrelevant every day, that it could easily be superseded by a new, better review, Cochrane or not. Changing the publication date, the 'old wine in new bottles' trick is certainly a clever trick. But, it is also a trick that it is...

We have posted a new petition update: Cochrane abandons the replacement review 19 Dec 2024 Cochrane cancels the review update A year after Hilda Bastian's last update from the Independent Advisory Group, and months after she last responded to any posts on her talkpage, Cochrane has made the...

Just a summary of the NIH ME/CFS study I think this bit got a bit garbled - Walitt's infamous quote gets another run: —by Brian Doctrow, Ph.D.

That study, also by Oxford Nanopore, is looking at epigenetics. A large-scale epigenetic analysis would be another very useful ME/CFS study. What I like about the latest ME/CFS study announcement, aside from the rather important possibility of it telling us something useful about the disease...

I wonder if it would be possible to offer a commercial service that could subsidise the project analyses? I mean, it sounds as though Oxford Nanopore is a private company, and Edinburgh Innovations exists to commercialise UofE innovations. So, could a whole genome genetic reporting and...

Cochrane's standing in the world of clinical guidance has been taking quite a hit. And with each year that passes, and with the strengthening of the acceptance of ME/CFS as the disease name, a 2019 review of exercise for chronic fatigue syndrome becomes more and more irrelevant. I think a new...

The more I think about, the more I think the announcement of the timeline for the Australian NHMRC ME/CFS Guideline is likely to have played a part in this. It's a really slow process - some 4 years. Paul Glasziou is likely to be having some say in what the NHMRC does - he was an author of the...