That sounds about right to me. It took about 4 years before I was tested to rule out an endocrine disorder, and that was as a result of a lot of pushing to get seen by a specialist (an infectious diseases specialist, by chance). My cortisol and ACTH response were fine, but I think people with...
It is interesting - to get statistically significant results with such a small sample suggests that there might be something here.
The researchers paid attention to pre-testing factors that might confound things e.g. the matching of participants and
I thought salt intake might differ, as...
I'm sure you are right. But they suggest that this paper is important. It is far from the first paper to find symptom overlaps between Long Covid (or at least a subset of Long Covid) and ME/CFS. And other papers have done a better job of describing that overlap.
Thanks @Purple and welcome to the forum. Do you have an association with this study?
I agree. With the added complication of there being not just one group of people with one illness, but a range of health conditions that are currently lumped under various post-Covid-19 names.
The abstract...
Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder? 2022 Azcue et al
A paper from people associated with some Spanish hospitals.
My impression of the situation in Spain is that that country might be worse than the UK in terms of the predominance of BPS...
I totally agree @Ravn.
This study is naive at best, I thought it would be someone's Masters project. But there are 15 authors. With that conclusion that Ravn quoted and the fact that the authors appear to be associated with Spanish hospitals and therefore able to influence clinical practice...
Brilliant @Subtropical Island, I think many of us have had similar experiences. If you do feel the need to delete your post, I hope you will keep it somewhere, perhaps on a Members Only thread, perhaps just for you, maybe to reuse one day.
Health-related quality of life and functional limitations after Covid-19
"Health-related quality of life by the 12-item short form survey (SF-12), calculating the mental component (MH) and PA domain scores."
[PA is physical health]
"Functional limitations after Covid-19 were calculated using the...
Selection
There was a high level of self-selection of participants, via social media and GP referral, so only those participants who were comfortable with the idea of physical training would have signed up. Participants needed to have had symptoms for 3 months, but that means that still a lot...
I think it's time the UK Office for National Statistics got a bit more sophisticated. It should be referring to post-Covid-19 effects, or post-acute Covid-19 symptoms, or something like that, because it is reporting the prevalence of a range of post-acute illness effects.
There is a lot of...
Long COVID and return to work: a qualitative study 2022 Kohn et al
This study, unfortunately paywalled, is from the Belgian Healthcare Knowledge Centre.
https://rarediseases.org/rare-diseases/stiff-person-syndrome/
The symptoms of Stiff Person syndrome sound a lot like what is diagnosed as a functional movement disorder:
fluctuating muscle pain, spasms, weakness and rigidity.
Testing isn't definitive.
If I developed these symptoms, I'd be...
Cortisol levels - results are in ug/dL (or mcg/dL)
Normal ranges for samples at 8 am are 5 to 25 ug/dL
There were only 13 male patients, so not really enough for a good result. Cortisol levels were not statistically different
Controls 15.1; Patients 14.2 p=0.61
There were 130 female...
Me too. Some people report feeling better with some OI medications that increase blood volume, but our thread on fludrocortisone does not suggest a great response, with a lot of people saying there was no effect or they felt worse.
An ongoing issue in microcirculation might be the problem to...
I think the paper is interesting, in strengthening the potential connection between problems in microcirculation and problems in macrocirculation and OI. I think some of the statements made are a bit of a reach, given the quality of the evidence for them.
I do like the fact that the hypothesis...
Same. Of course it makes sense, but it's not something I had ever thought of.
The authors say:
And here's their hypothesis in a vicious cycle diagram:
I'm not sure about some of the assumptions there. For instance, what evidence is there for increased blood cell size? I'm pretty sure...
So, if the veins aren't able to contract because muscle cells around them aren't receiving oxygen and nutrients, then the circulatory system can't properly function to get enough blood back to the heart. Muscles generally may get fatigued and painful because they aren't receiving enough oxygen...
Some notes as I read
As background: here's an image of the vasa vasorum. Capillaries help supply oxygen and nutrients to the cells of the arteries and veins. They are particularly important in veins, because the veins are carrying blood that is low in oxygen and nutrients and the blood is...
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