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More inappropriate titles. "We lost our keys, we looked in just two places, the keys weren't there, so the keys are lost forever and cannot be recovered"

People with "psychological flexibility" answer differently on scales. But these people don't understand what scales actually measure so they're confused.

This is awful.

Here is the thing, I don't consider daytime sleepiness to be a core symptom of ME/CFS. I have to sleep a lot (10-12 hours), but my usual symptoms are not daytime "tiredness"/"sleepiness", it's physical fatigue, brainfog, permanent headache etc. any orthostatic symptoms for me are only ever a...

ME/CFS is not simply a list of vaguely defined symptoms. It's not just sleep doctors but doctors who focus on ME/CFS who can tell the difference. "Tiredness" in particular can mean very different things. The tiredness that a UARS patient experiences is quite different (since it is usually due...

I don't think ME/CFS is a single disorder either, due to the lack of specificity of the diagnosis method, but UARS presents quite differently to ME/CFS in terms of symptoms. Some doctors may well misdiagnose it (ME/CFS instead of something else like UARS) because doctors often make mistakes but...

It's barely studied at all unfortunately. There is some discussion here: https://www.mdpi.com/1422-0067/23/19/11852

I checked and yes, the other divisive subject is his transphobia because of course... The interesting thing is in one case (ME/CFS) the patients are against treatments due to poor quality evidence, in the other case he is trying to say that patients should not be treated due to lack of quality...

There is a lot more than expectancy biases too, but yes I agree he seems to deliberately ignore all of the biases.

They mention an altered O-glycosylation pattern but don't say what the pattern was. The following links to Davide Ret's overall project: https://mrr.mecfs-research.org/en/persons/aY0rj6w-TCOaiyBTqRlpjQ https://www.wwtf.at/funding/programmes/ei/ME-CFS24-016/

I guess the word putative isn't as popular anymore.

Yeah nah. There is almost no evidence for that.

This is a problem in so many psychology studies on so many different topics.

Yes, they've skipped the relapse-remitting onset pattern and it's disappointing.

Classic confusion of directionality between cause and effect

Yes.

Well the cited "not science-based" Bessel van der Kolk are bad pseudoscientific writers. The former wrote the junk book "The Body Keeps the Score", and the latter of https://en.wikipedia.org/wiki/Somatic_experiencing fame, and wrote his thesis on how stress causes symptoms...

It's a non specific symptom with numerous causes, I wouldn't get too excited about such an association.

UK Labour is no longer a centre-left party that considers peoples needs over the wealthy. It's a deep shame they passed this.

I forgot about this thread. One of the popular hypotheses (of efficacy) is around TLR4 antagonism which putatively can lead to pain sensing nerve densitisation. I'm not sure why it makes some people worse, it may be the base opioid receptor antagonism