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Dr Nicola Clague-Baker on Twitter "A heavily edited letter that we produced in response to the New Scientist article - https://newscientist.com/letter/mg26134790-900-on-the-use-of-exercise-therapy-for-long-covid/" On the use of exercise therapy for long covid Published 21 February 2024 From...

A snippet of interest for @Hutan "Salivary cortisol measurements taken at rest in the morning, at noon, and before sleep showed no group differences but were significantly lower in PI-ME/CFS participants one hour after CPET"

Scientists find link between brain imbalance and chronic fatigue syndrome https://www.theguardian.com/society/2024/feb/21/scientists-find-link-between-brain-imbalance-and-chronic-fatigue-syndrome

"Case adjudication Clinical information from the visit was compiled and reviewed by a Case Adjudication panel. Adjudicators were all recognized clinical experts in ME/CFS (Lucinda Bateman, Andy Kogelnik, Anthony Komaroff, Benjamin Natelson, Daniel Peterson). Each adjudicator performed their own...

They are saying that we choose not to do something because we perceive it as too much effort.

"Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is the commonly used term to describe a disorder of persistent and disabling fatigue, exercise intolerance, malaise, cognitive complaints, and physical symptoms with significant socioeconomic consequences." Even this is word salad. No...

Just to highlight that the link in this section of the update is broken, "An update from the Cochrane IAG There was an update from Cochrane's Independent Advisory Group for the planned new review on 20 December 2023 - available here "

https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review Current total is 10,536.

Science Media Centre: expert reaction to study of deep phenotyping of patients with post-infectious ME/CFS Quotes from Dr Karl Morten, Prof Chris Ponting, and Dr Katharine Seton https://www.sciencemediacentre.org/expert-reaction-to-study-of-deep-phenotyping-of-patients-with-post-infectious-me-cfs/

NIH Press Release NIH study offers new clues into the causes of post-infectious ME/CFS In a detailed clinical study, researchers at the National Institutes of Health have found differences in the brains and immune systems of people with post-infectious myalgic encephalomyelitis/chronic fatigue...

"To be considered an adjudicated case, participants were required to be unanimously considered to be a case of PI-ME/CFS by the protocol’s adjudication committee, meet at least one of three ME/CFS criteria (1994 Fukuda Criteria64, 2003 Canadian Consensus Criteria for Myalgic...

Program is here, https://www.fndsociety.org/biennial-meeting/2024/program Includes such delights as What Makes a Good Therapy Candidate and Setting Up an Initial Treatment Plan Sarah C. Lidstone, MD, PhD; Glenn Nielsen, PhD; Sepideh Bajestan, MD PhD; and Jason David Kreuzman, OTR/L Treatment...

Thread for paper here, Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome, 2024, Walitt et al

Abstract Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a disabling disorder, yet the clinical phenotype is poorly defined, the pathophysiology is unknown, and no disease-modifying treatments are available. We used rigorous criteria to recruit PI-ME/CFS...

This post has been copied and the following posts moved from the main thread on the study: Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome, 2024, Walitt et al Abstract Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a...

This post has been copied and many following posts moved from the main thread on the study: Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome, 2024, Walitt et al Abstract Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a...

How the Immune System Fights to Keep Herpes at Bay https://hms.harvard.edu/news/how-immune-system-fights-keep-herpes-bay

Significance Upon viral infection, cells produce and secrete proteins called interferons (IFNs) that bind to receptors on infected or neighboring cells to induce the expression of genes whose products act to interfere with viral replication. The mechanisms of action of certain of the IFN-induced...

Trial By Error: New Long Covid Exercise-and-Therapy Study Claims Success Despite Clinically Insignificant Findings A new study of an online group physical and psychological rehabilitation program for Long Covid confirms once again that people given an intervention purporting to help them are...

https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review Current total is 10,522.