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  1. Andy

    Pediatric and Adult Patients with ME/CFS following COVID-19: A Structured Approach to Diagnosis Using the MBSQ, 2023, Peo et al.

    Lenny Jason is now added to the list of authors, Laura-Carlotta Peo, Katharina Wiehler, Johannes Paulick, Katrin Gerrer, Ariane Leone, Anja Viereck, Matthias Haegele, Silvia Stojanov, Cordula Warlitz, Silvia Augustin, Martin Alberer, Daniel B. R. Hattesohl, Laura Froehlich, Carmen...
  2. Andy

    Long-term outcomes following hospital admission for COVID-19 versus seasonal influenza: a cohort study, 2023, Xie, Al-Aly et al.

    ‘Long flu’: study finds flu patients at higher risk of longer-term illness "People who have been hospitalised with flu are at an increased risk of longer-term health problems, similar to those with long Covid, data suggests. While the symptoms associated with such “long flu” appear to be more...
  3. Andy

    GDF15 linked to maternal risk of nausea and vomiting during pregnancy 2023 Fejzo et al (hyperemesis gravidarum - morning sickness in pregnancy)

    Of possible interest is this study, Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome, 2019, Melvin, Lacerda, Nacul et al
  4. Andy

    GDF15 linked to maternal risk of nausea and vomiting during pregnancy 2023 Fejzo et al (hyperemesis gravidarum - morning sickness in pregnancy)

    Extreme morning sickness? Scientists finally pinpoint a possible cause "Researchers have pinpointed a hormone released by growing fetuses that might cause a debilitating form of morning sickness. Women who are more sensitive to the hormone, which increases during early pregnancy, might be at...
  5. Andy

    GDF15 linked to maternal risk of nausea and vomiting during pregnancy 2023 Fejzo et al (hyperemesis gravidarum - morning sickness in pregnancy)

    Merged thread Abstract GDF15, a hormone acting on the brainstem, has been implicated in the nausea and vomiting of pregnancy (NVP) including its most severe form, Hyperemesis Gravidarum (HG), but a full mechanistic understanding is lacking [1-4]. Here we report that fetal production of GDF15...
  6. Andy

    Regulation of stress-induced sleep fragmentation by preoptic glutamatergic neurons 2023 Smith et al

    Neurons responsible for poor sleep and stress found in mice "Researchers have now identified a group of neurons in the brains of mice that are involved in regulating blips of wakefulness, called microarousals. The finding1 could help to explain how stress disrupts sleep, says Ketema Paul, a...
  7. Andy

    Regulation of stress-induced sleep fragmentation by preoptic glutamatergic neurons 2023 Smith et al

    Highlights POA glutamatergic neurons become activated during microarousals in NREM sleep Stress activates POA glutamatergic neurons, leading to fragmented sleep Inhibiting POA glutamatergic neurons attenuates stress-induced sleep fragmentation Presynaptic inputs in the lateral hypothalamus...
  8. Andy

    Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition 2023 Gerrick et al

    This group of bizarre gut microbes is unexpectedly complex "Alongside the bacteria, fungi and other organisms living in our guts are single-celled, nucleus-bearing microorganisms called protists. A study in mice — whose protists are related to some found in humans — now shows how these...
  9. Andy

    Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition 2023 Gerrick et al

    Highlights Metabolic diversity in protists drives convergent Th1/Th17, but divergent Th2, immunity Protists’ preference for fiber or mucus shapes trans-kingdom competition with bacteria During fiber starvation, bacteria outcompete Tmu for the mucus niche Dietary fiber composition can modulate...
  10. Andy

    Routine outcomes and evaluation of an 8-week outpatient multidisciplinary rehabilitative therapy program for FND 2023 Guy et al

    I use a service called Stork, https://www.storkapp.me/main.php, which finds me papers newly published that match certain keywords every day. I would be more than happy not to have to monitor what the FND folk are publishing but I believe that they present a real danger to our patient community...
  11. Andy

    Routine outcomes and evaluation of an 8-week outpatient multidisciplinary rehabilitative therapy program for FND 2023 Guy et al

    "The themes of these sessions included: behavioral activation and gradually increasing activity, managing ‘boom-and-bust’ patterns, goal setting, strategies to overcome worry, managing anxiety, sleep hygiene and fatigue management, communication styles, volunteering, and relapse prevention...
  12. Andy

    Routine outcomes and evaluation of an 8-week outpatient multidisciplinary rehabilitative therapy program for FND 2023 Guy et al

    Looks like possibly another for you @dave30th ? "Functional neurological disorder (FND) refers to genuinely experienced neurological symptoms that cause significant distress or disruption, without evidence of an underlying neurological, psychiatric or other medical explanation [1, 2]. FND has...
  13. Andy

    Routine outcomes and evaluation of an 8-week outpatient multidisciplinary rehabilitative therapy program for FND 2023 Guy et al

    Abstract Objectives We report routinely collected outcome data from an 8-week outpatient rehabilitative therapy program. The aims of the intervention were to (1) reduce symptom severity and (2) improve functional mobility in adults with functional neurological disorder (FND). Methods The...
  14. Andy

    Organisation: International Patient and Public Involvement Network

    Yeah, with him involved my basic assumption is that this is more a talking shop than anything that actually gets stuff done.
  15. Andy

    Review Psychological interventions to improve ... hypermobility spectrum disorders and Ehlers-Danlos syndrome... 2023 Clark et al

    The corresponding author, Katherine Swainston, also had the same role for this study, What psychological interventions are effective for the management of (PPS)? A systematic review and meta-analysis, 2022, Swainston et al She is listed as based at Faculty of Medical Sciences, Newcastle...
  16. Andy

    Review Psychological interventions to improve ... hypermobility spectrum disorders and Ehlers-Danlos syndrome... 2023 Clark et al

    Full title: Psychological interventions to improve pain, fatigue, anxiety, depression, and quality of life in children and adults with hypermobility spectrum disorders and Ehlers-Danlos syndrome: a systematic review Abstract Hypermobility spectrum disorders (HSD) affect individuals across...
  17. Andy

    Developing and validating a brief screening scale for ME/CFS, 2023, Jason et al

    I would assume, based on their previous work that "Minimum exercise makes you physically tired" is meant to be asking about PEM.
  18. Andy

    Organisation: International Patient and Public Involvement Network

    Who are we? In 2017, a number of organisations and individuals from across the globe came together to form the International Patient and Public Involvement (PPI) Network. We believe that through the International PPI Network we can join together and enhance the opportunities such a network would...
  19. Andy

    USA: NIH National Institutes of Health news - latest ME/CFS webinar 14 Jan 2025

    Registration is available for the next webinar. Less Studied Pathologies: ME/CFS Research Roadmap Working Group of Council Webinar 7 of 8 - Jan 5, https://roseliassociates.zoomgov.com/webinar/register/WN_c0WYA2I6SRyV_nBGpSWWGw#/registration Ilene Ruhoy MD PhD posted on Twitter "Register now...
  20. Andy

    Developing and validating a brief screening scale for ME/CFS, 2023, Jason et al

    I would guess the value of this will depend on what use case they see for "a brief screening instrument". If it is intended to definitively identify ME/CFS then yes, that would be problematic; if it is intended as a list of questions to ask before a full investigation of symptoms then it might...
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