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Did you do a 60 minute test to investigate heart and lung function using ecg? Or a shorter 10-20 minute maximal cardiopulmonary test (intended to reach your peak heart rate and oxygen consumption)? When you say an increase of 6%, what exactly was increasing?

They seem terribly confused about the purpose of rehabilitative approaches. Graded exercise is worthwhile as rehabilitation post-covid for patients that are NOT suffering from LongCovid, but merely residual deconditioning and pulmonary impairment.

Did you objectively measure your activity levels before and after (with a fitbit or similar?)

Of course you can, it's called meta-analysis and it's common.

Twitter polls of longcovid patients suggest most are not improving after the vaccine. Still, if there is genuine improvement in a minority, it does suggest immune system involvement in the perpetuation of the illness.

Probably the number of medical practitioners who were affected all at once.

Seems rather odd that the "opponent" presents part of the thesis!?!

It's not the sitting per se, but the staying in one position for a long period of time. Standing on the spot without moving much also poses the same problems.

The study suggests that IDO1 inhibition in dendritic cells leads to increased T cell proliferation, in cases where there is no direct cell-cell contact. In the context of the study, this is portrayed as a positive phenomena, which is contrary to Phair's hypothesis. They also observed no change...

But, but, there is more than one problematic part of that sentence!

It can be problematic if researchers have never bothered to ask patients if they believe the questionnaires are relevant or of high quality. (which an unfortunate flaw of most questionnaire based studies) If it is about how patients feel, I'd prefer a qualitative study, not a bunch of...

https://ashpublications.org/bloodadvances/article/5/5/1305/475250/The-SARS-CoV-2-receptor-binding-domain Well, not exactly. The authors state: They used a glycan array assay - they didn't actually observe differences in binding to real lung cells. Also note that spike protein binding to...

But they're not actually measuring any real evidence of "CSS" they're just using questionnaires and pretending this is evidence.

Who cares? We're pointing out the methodology sucks.

More questionnaire junk. 'Central sensitisation' needs actual neurological evidence.

The headlines are potentially misleading. None of the data is generalisable, but merely of suggestive evidence due to non-random selection of participants. The length of followup data is too short and the AZ data is particularly limited in sample size. Efficacy for both vaccines was in the 60%...

All this illustrates is the lack of specificity of either the criteria or the questionnaires. Only with understanding of the underlying pathology can they be truly linked.

I think this is worth studying, though I don't think the authors of this review really understand the relationship between the benefits they cite "muscle atrophy, improve muscle strength and function, maintain blood flow and reduce oedema". Cardiovascular fitness will still decline even with...

The 94% figure is nonsense, lacks sufficient sample size to have any confidence for generalisation. Have a look at the data in the appendix. The efficacy in the first few weeks of both vaccines (against hospitalisation) is in the 50-75% range) But there is a lack of data for the AZ vaccine in...

I'd just like to comment on the frequent claims in the media that all of the vaccines "prevent" severe illness and death. Unfortunately, this is not true. The clinical trials did not have sufficient sample size for any conclusions on this. However real-world data shows that while the risk is...