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I think this is the paper they mention: Development and evaluation of blood-based prognostic biomarkers for COVID disease outcomes using EpiSwitch 3-dimensional genomic regulatory immuno-genetic profiling, 2024, Hunter et al

"Dr. Hendrich will present more findings from his #LongCovid PET and biopsy study at PolyBio’s upcoming symposium:" Zoom link (Nov 8, 2024, 4:00 PM GMT)

A comment on PubPeer has some similar criticisms as what @Trish said.

I'd say it's safe to put no then. Mostly I was checking for it barely being noticeable for any ailment in other people.

Oh I meant like I'm not sure how much this is a PEM-related symptom or an all the time symptom.

I think I get sick pretty rarely. In the past 5 years, I've probably had 5 or so significant infections, with runny nose, sore throat, and worsened fatigue, and I think 4 of those were COVID. Maybe some more mild ones that only last a day or two. When the people I live with get sick, I barely...

Oh, I wanted to see if what I experience of only getting relief from ibuprofen, but not the other two is common. Maybe it would have been better to ask if none of the three work, I'm not sure.

Finding Long-COVID: temporal topic modeling of electronic health records from the N3C and RECOVER programs Shawn T. O’Neil, Charisse Madlock-Brown, Kenneth J. Wilkins, Brenda M. McGrath, Hannah E. Davis, Gina S. Assaf, Hannah Wei, Parya Zareie, Evan T. French, Johanna Loomba, Julie A. McMurry...

Long COVID as a Possible Contributor to Rising Suicide Mortality in Bharat (India): An Analysis of Suicide Trends Since the Emergence of COVID-19 Karan Varshney, Mansoor Ahmed Panhwar Abstract Mortality due to suicide is amongst the largest public health concerns across the world today in...

Here are those 12 SNPs that overlap between ME/CFS and both LC groups. Fully bolded SNPs were labeled as critical in both long COVID cohorts. Ones with an F or S were critical in only the fatigue or severe cohort. ATP9A: rs6096573 ATP9A: rs77771672 GPC5: rs1536620 (F) GPC5: rs17267214 GPC5...

I'd say just vote No, since the paracetamol at least does something.

Ok, poll is up.

Yeah, I think you're right.

Hmm, not sure. I guess mainly what I wanted to see was if this might be a common thing in ME/CFS: that Tylenol and aspirin don't work for anything, while ibuprofen does. Doesn't sound like anyone has said anything similar yet though, so probably not.

I don't know if that's necessary since the question is specifically about the three painkillers listed.

Might be better for someone who experiences that symptom to word the question to do it justice.

Made a thread to move the discussion to: Painkiller effectiveness for people with ME/CFS

Following up on a mini discussion here: I'll make a poll on this thread to see if there's some trend toward one painkiller being more effective for people with ME/CFS. I've always thought it was interesting that aspirin and Tylenol seem to do nothing for me, at least at recommended doses...

A long Phoenix Rising thread about this. From what I recall, only a few found some relief, but it was more than one person at least: Cumin (Cuminum cyminum): Possible PEM Blocker

Sure, do you think this wording would be good: For those with ME/CFS: Of these painkillers, are any of them significantly more effective for your pain than the other two? * Ibuprofen (Advil) * Acetominophen (Tylenol) * Aspirin * No single painkiller stands out as better than the other two.