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Microglia Transcriptional Profiling in Major Depressive Disorder Shows Inhibition of Cortical Gray Matter Microglia https://www.biologicalpsychiatryjournal.com/article/S0006-3223(23)01239-8/fulltext Biological psychiatry Microglia have been implicated in the pathophysiology of major depressive...

Oh, we're at the stage where 14% can be preceded with the qualifier "only", uh? Quite a change from the starting position that this wouldn't happen at all, and that even 10% was vastly overblown, mocked as ridiculous, as scaring the common folk into manifesting that very illness. Somehow. Even...

Spending money is a good way to save money. Turning on a heater is a good way to cool a room. Freedom is slavery. These people are delusional. They say delusional things. They can't possibly not understand that this is delusional. And yet here we are. They have no tests for this. They don't...

This is such a meaningless term. The treatments are not effective. It is known that they are not effective. It is not the depression that resists treatment, it is the treatments that are not effective. Medicine is badly in need of soft skills. And however soft psychological skills may be...

Many countries have rules for advertising that explicitly forbid this kind of misleading language and tactics. Not that it doesn't happen in private, but at least it's explicitly not allowed, certainly not encouraged. Advertising has stricter rules than health care when it comes to telling the...

Nice. Have just skimmed to get the general idea, but this looks a lot like what I proposed a while ago. Actually looking for it, 4 years. Ugh. Time passes, and life with it. From a thread about a similar scale called the Validation of the Pittsburgh Fatigability Scale. This is something that...

It's cute when they borrow expressions used by people who actually do stuff. More like rusty wooden knife edge.

And since this morning I've had a depressing thought about who would get that money for that research. The very same people, of course! I mean who else could do this research if not for the very same people who have years of experience with it? This is like debunking Theranos' research and...

It could jeopardize an entire industry's massive revenue streams. That is urgent. To them. It's rare to find jobs that pay that well and require so little effort.

A Systematic Review of Persistent Clinical Features After SARS-CoV-2 in the Pediatric Population https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2022-060351/192816/A-Systematic-Review-of-Persistent-Clinical AAP Pediatrics OBJECTIVE: To present the prevalence and...

Yeah, the absolute saddest thing is that, yes, NLP has been subject to the same standard of scientific rigor as CBT. That's the saddest part about it. Far less of it, of course, in terms of resources spent, but the standard is the same. Because it's a much smaller industry, but it is very much a...

I'm not sure if this is a good analogy since when the Rosetta Stone was found it had a rapid impact, experts recognized it for its major importance. Maybe not immediately immediately, but it definitely did not take decades of ignoring it, then several more years after it was identified properly...

"I'm not gaslighting you, I'm negotiating you", says the gaslighter, trained, by gaslighters, not only in gaslighting but in gaslighting about gaslighting, which is gaslighting, about gaslighting, to the gaslit, with a large "No gaslighting allowed" sign looming behind. "Don't you mean...

Oh, well, this is a disappointing, and downright bizarre, conclusion. This is obviously not what's needed, it's clearly not going to change minds, and it means more money wasted to feed egos and businesses that could be put to better use elsewhere, although the latter is probably not very...

As we know, many actual journalists, and editors, from major publications, did back down from threats by Wessely and his gang. And likely elsewhere. Although it's hard to say whether he could have stormed this if his father was not chief White House correspondent for the New York times, and...

Keep in mind that the identified fraud was over copied images, if I understand it correctly. Not exactly disputable when you're caught. Just as disputable as overlapping entry and recovery criteria. And yet, hubris and bullying.

Familiar behavior. Actually, identical behavior. (Asking Theo Baker, the journalism student who caused the resignation)

Unfortunately, not a thing. There are no high-quality studies of this, only ones that aren't impossibly biased or plain silly. Which is why this New Age stuff was always bunk. But whatever the point stands. And why would this even work? It makes no sense whatsoever. We are complex beings living...

The pattern where it's worse in context, and the more context you add, is still holding up perfectly. There are layers and layers of malfeasance and blatantly unprofessional behavior, although clearly it's not even unique or particular to us. Modern academia reminds me too much of old...

A belief that has resisted the onslaught of Long Covid where most patients have reported doing exactly that, and more. The main problem with psychiatry and psychosomatic medicine is that they don't listen. At all. Never. They will tell a patient to exercise. The patient will respond that they...