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  1. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    Sounds sensible and efficient. With the case reports, we’re currently just using consumer grade wearable fitness trackers. eg.
  2. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    It’s very much like the “metabolic trap” and explains a lot of Fluge’s work. Essentially, both of those papers bolt directly into this disease model without any alteration and directly extend it. For the purposes of being responsible to the wider community, we intentionally did not spell out...
  3. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    Thank you, Jon - truly. This is the type of conversation I came here to participate in. Appreciate your comment. To clarify, in those early paragraphs, I'm aware of the research-use of EBV to transform b-cells for this purpose. Rightly, or wrongly, I was trying to tie Fukushima's work to EBV...
  4. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    I would do 2 NutraEval tests on the same day - One of them, fasted, AM. The other mid-afternoon at the time where symptoms normally worsen. Ideally this would involve a day with enough activity to produce a snapshot of the 'fault' state.
  5. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    Frankly, I'm feeling insulted. I hear claims of 'pseudoscience' and 'homeopathy', yet an unwillingness to understand or test the model. Failure to test and repeat something is pseudoscience.
  6. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    I guess you could always test it, instead of making assumptions.
  7. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    I’m not sure if you noticed the part where I haven’t charged a single CFS/ME client during this entire 6 month process and worked full time, around the clock. The research has been entirely unfunded and done out of human interest. The patent was filed after I saw positive results for every...
  8. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    Metabolic studies will be confounded by the disparity between the time of day that samples are taken and relative to previous activity levels. A simple and unpleasant way to control for this is requiring a specific amount of exertion to induce PEM being the criteria before pulling a sample...
  9. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    I did try contacting key people in OMF around November last year. Multiple emails and a message via ResearchGate. We recently forwarded them a link to the preprint, so it’s possible we may see a response from this.
  10. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    I’m sorry if the 43 pages I took to describe the model was insufficient to communicate the mechanisms involved. I was able to piece together multiple results from other researchers from different fields to provide a testable model. I’d be more than happy to share a test protocol with anyone...
  11. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    I can understand your skepticism, given the amount of research everyone has already placed into this. However, the cost of testing this per patient, is roughly $5 worth of treatment protocol and $x amount of pathology. I'm not seeing the cause for concern.
  12. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    Thanks for the warm welcome, Mario! 1) I haven't specifically tried applying known reported "flox" symptomology (this area is not widely represented in literature), however 2 of my clients had also reported being 'floxed'. They each had EBV lytic infections. 2) It's about 90% common, with...
  13. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    The background on this discovery is that in the course of my normal consulting, I had a cluster of 5 diet coaching clients over roughly one month presenting for a number of different goals, yet similar issues - with a common complaint of daytime fatigue. Most had joint pains and involuntary...
  14. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    No, but we have filed a patent based on the method.
  15. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    Hi John, I understand where you're coming from. I think you might be focusing on the wrong aspects of the paper. What I demonstrated was a model where any 1 of many situations causes the same "loop" and state. I also demonstrated how that would happen from a non-HHV source, eg. C.diff...
  16. J

    Preprint The true nature of an autoimmune disease, Leisk and Nocon 2021

    Hi All, Author here. Happy to help! > If herpesviruses are at the root of ME/CFS, then how come we are currently amidst a long-covid (which is almost certainly CFS) epidemic caused by a coronavirus? Hypoxia from COVID-19 triggers reactivation of EBV. > I don't think this is worth spending...
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