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  1. rvallee

    Closed UK: DecodeME updates, was recruitment thread.

    This makes me wonder whether this was asked of PACE participants. The authors made a big deal of hiding the data because of the potential for abuse, which as it turned out was completely unfounded, but we don't know what PACE participants agreed to. I wouldn't be surprised if similar % agreed to...
  2. rvallee

    Trial Report Factors associated with having previously received a diagnosis of fibromyalgia, CFS and IBS: A cross sectional DanFunD study,2024,Tattan/Fink/Rosmalen

    So, what is even the point of this? It adds absolutely nothing, there have been many poorly done studies like this before and they pretty much all show the same thing: nothing. Apply bad questionnaires, get useless responses. This is so obviously just bad researchers being gifted yet another...
  3. rvallee

    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    Well, the good thing is that it's very unlikely that it continues existing more than maybe 5 years, AI will replace all of this useless industry. They add nothing whatsoever to the process, being a garbage in-garbage out process.
  4. rvallee

    Sense about Science: Join our talks on science, scepticism and free speech (Garner et al)

    Pretty much overwhelmingly you find the same thing as well in LC: mornings suuuuuuck, are the worst time of day. I've never heard of people feeling various horrible, then had fantastic days, then back. Some better days, but definitely not "absolutely fantastic". Can still be a thing, but it'd be...
  5. rvallee

    Sense about Science: Join our talks on science, scepticism and free speech (Garner et al)

    Impressive jumble of selective memory and a very odd perspective on things. But I guess this explains why Cochrane has effectively shut down the process while pretending otherwise. I'm sure he believes this is what happened. Or whatever. But he has mixed some comically wrong misinterpretation...
  6. rvallee

    What are the necessary conditions and criteria for a theoretical model of ME/CFS?

    I think this is the more useful exercise. Not a model per se, but a list of what can exclude potential models because they contradict reliable data. And hopefully not a done-soon thought experiment, but one that is refined with time as we get more data. We still haven't seen any of the RECOVER...
  7. rvallee

    What are the necessary conditions and criteria for a theoretical model of ME/CFS?

    I'll see where the discussion goes and try to keep track of what comes out. I can't really do this on my own, just hoping this generates enough discussion and refinement to have a few items no one can poke holes in.
  8. rvallee

    USA Centers for Disease Control (CDC) news (including ME/CFS Stakeholder Engagement and Communication Calls) - next call 4 Dec 2024

    Treatable doesn't mean we know how to treat it, it just means that it can be treated, there is nothing permanently lost or unfixable here. People recover after years of illness. It's rare, but it is possible to treat it. Knowing how is a different issue, but we are not stuck like some diseases...
  9. rvallee

    Artificial intelligence in medicine and science

    Use of a Large Language Model to Assess Clinical Acuity of Adults in the Emergency Department https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2818387 Key Points Question Can a large language model (LLM) accurately assess clinical acuity in the emergency department (ED)...
  10. rvallee

    UK: Disability benefits (UC, ESA and PIP) - news and updates 2024 and 2025

    This is the same level of brain-dead thinking that has led to the whole nonsense about GPs "prescribing" walks in the park and other stuff that has nothing to do with the role of health care. We keep seeing again and again how enjoying life is the best way for people to have quality of life and...
  11. rvallee

    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    At this point, I don't know who could do that work, but I would find it worth highlighting that probably over 80% of the major associations, charities and organizations dedicated to ME/CFS support this, and support a biomedical-only approach. And that's probably an undercount. Depending on...
  12. rvallee

    USA Centers for Disease Control (CDC) news (including ME/CFS Stakeholder Engagement and Communication Calls) - next call 4 Dec 2024

    As disappointing an answer as it might be, I maintain that pharmaceuticals have a huge interest in being involved, and not in the future, now. This is an illness that anyone can develop at any age, is obviously treatable, given that spontaneous recoveries happen, and is not about to go away, as...
  13. rvallee

    Multidisciplinary Management Strategies for Long COVID: A Narrative Review, 2024, Qu et al

    Not sure how important this CureUs thing is, but this review is mostly the same old, recommending exercise, CBT and pacing, with generic rehabilitation as the overall model. There is talk of activities being symptom-titrated, but with the goal of increasing intensity as a treatment, which...
  14. rvallee

    Multidisciplinary Management Strategies for Long COVID: A Narrative Review, 2024, Qu et al

    Multidisciplinary Management Strategies for Long COVID: A Narrative Review https://www.cureus.com/articles/233994-multidisciplinary-management-strategies-for-long-covid-a-narrative-review#!/ Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of infections to date...
  15. rvallee

    The People's Pharmacy: Mending Mistrust–Can We Rebuild Faith in Medicine?

    The balance of information has changed massively. The balance of power remains the same.
  16. rvallee

    News from Canada

    Not sure how useful this would be, but it's probably better than nothing, or an example I saw recently, a problem that only affects teenage girls. It's the tiniest bit of progress anyone could imagine, only short stop removed from "doesn't exist". But that's medical progress for you. There is...
  17. rvallee

    Different kinds of abnormalities of heart rate and blood pressure

    "novel" Overall not bad, but has significant limitations. They notice a common co-morbidity with ME/CFS, but under special considerations make no mention of PEM/PESE and how it should be a contraindication from their primary recommendation, which is, you guessed it: regular aerobic exercise...
  18. rvallee

    What are the necessary conditions and criteria for a theoretical model of ME/CFS?

    What's more important about a good model isn't so much that it accounts for all things, but allows for them, makes sense of them. A model accounting for every detail would probably be too complex, it has to be distilled into its most fundamental components. But as long as it makes sense of the...
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