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  1. rvallee

    United Kingdom News (including UK wide, England, NI and Wales - see separate thread for news from Scotland)

    Interesting debunking of blatant misrepresentation of Long Covid data from the UK national survey. None of this can be argued to be accidental, it's very deliberate manipulation of perception. It clearly aims to misrepresent the lie that most people who would go on to develop LC already have. We...
  2. rvallee

    BioVie Awarded up to $13.1 Million in Funding from U.S. Department of Defense to Evaluate Bezisterim (NE3107) for the Treatment of Long COVID

    The US army has a loooot of people on active or reserve duty and lots more in veterans affairs. On top of a huge number of civilians in the administration and support side of things. Even something with a 1-2% prevalence can have a lot of impact if it's fully disabling, requiring lots of complex...
  3. rvallee

    Trial Report Functional Limitations and Exercise Intolerance in Patients With Post-COVID Condition A Randomized Crossover Clinical Trial, 2024, Tryfonos et al

    The same old nonsense as always. The small study doesn't support this, but it's said anyway, because exercise was already obsessively pushed, though they frame this as though there has been a full stop on all recommendations, even though it clearly does not treat or improve the condition...
  4. rvallee

    Correcting the scientific record on abortion and mental health outcomes, 2024, Littell et al.

    Published in BMJ and cites COPE, which as we know has been ignoring issues with Cochrane's terrible reviews on GET, where authors somehow, sometimes, get a veto on not retracting because "nuh uh", and simply mumbling about how it's out of their hands. LMAO. It's things like this that makes it...
  5. rvallee

    Trial Report Phenylephrine Alters Phase Synchronization between Cerebral Blood Velocity and Blood Pressure in CFS with Orthostatic Intolerance,2024,Medow & Stewart

    Phenylephrine is a decongestant commonly found in some over-the-counter cold medication like Sudafed. Usually it's to reduce swelling and congestion in the sinuses, but apparently it works rather poorly for that when taken in pill form. Also apparently in some hemorrhoid medication, again to...
  6. rvallee

    Review Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches, 2024, Molnar et al.

    Oof. Not exactly encouraging... It's so poorly studied, and yet it may in fact be the most well-studied. Loooong way to go yet. I still get a strong feeling that once research produces significant breakthroughs here it will fuel a massive boost in medical science, basically uncovering many...
  7. rvallee

    UK: People with ongoing Long Covid symptoms unable to donate blood (as of July 2023)

    They're claiming whatever explanation satisfies the person asking at the moment they're asking.
  8. rvallee

    Trial Report Psychometric Properties of the REMAP Resilience Scale in a Norwegian Sample of ME/CFS Patients and Healthy Controls, 2024, Strand

    Also as I tend to be the polar opposite of almost every feature of the psychosocial stereotypes, this is yet another one. I'm a stoic by nature, it takes no effort for me to be 'resilient' in its usual meaning (as opposed to whatever is meant by this weird questionnaire, which includes questions...
  9. rvallee

    The Last Straw: How Stress Can Unmask Parkinson’s Disease 2024 van der Heide et al

    I don't think there's much confusion here. Rather it's preferring to think that a correlation must be causative because reasons.
  10. rvallee

    Trial Report Chronic nonspecific multiple-sites pain [CNMSP] of unknown etiology: Biopsychosocial method of evaluation for the primary care level, 2024, Goel

    This stuff is really the core of the problem. This needs no such thing. The biopsychosocial model is mostly useless, there is never a need for something that is useless. It's what the authors want, what is oddly fashionable despite being useless, which has nothing to do with what the patients...
  11. rvallee

    Practical Recommendations for Exercise Training in Patients with Long COVID with or without Post-exertional Malaise, 2024, Gloeckl, Scheibenbogen+

    Going back to this thread in the light of another where comments submitted for the NICE guideline by various medical bodies that rely on active rehabilitation were discussed, it's clear that one problem is that it's assumed that exercise is good for everyone all the time, and that more exercise...
  12. rvallee

    The Agreed Care/Activity Plan

    That framing has long been around, the idea that patients can choose to re-engage with the treatments later on, if they finally find the motivation for it. Yes, you've tried CBT and GET, but you can always try them again. And again. It works, if you have the motivation, has always been the core...
  13. rvallee

    The Agreed Care/Activity Plan

    I can't see it another way than that this is the same framing as in most psychotherapy, or addiction treatment, where this is explicitly demanded of patients that they actively engage in their therapeutic process. Which is consistent with the general idea that they may pretend that a biological...
  14. rvallee

    Trial Report Functional Limitations and Exercise Intolerance in Patients With Post-COVID Condition A Randomized Crossover Clinical Trial, 2024, Tryfonos et al

    So, the exact same thing, but with different words. Good grief. This is why the subject can't even be broached, that we basically have to categorically shut the door to it because even when it recognizes what's always been denied, PEM/PESE, they just want to do the same thing for the same reason...
  15. rvallee

    The Last Straw: How Stress Can Unmask Parkinson’s Disease 2024 van der Heide et al

    All of this makes a lot of sense when stress is used with its common meaning, typically an external force making a demand and requiring energy to return to its previous state, rather than the modern woo-woo definition misused in psychosocial ideology. Physicians have long advised ill people to...
  16. rvallee

    Trial Report Psychometric Properties of the REMAP Resilience Scale in a Norwegian Sample of ME/CFS Patients and Healthy Controls, 2024, Strand

    This is not an appropriate thing in ME/CFS, it's highly arbitrary and I can't think of a single possible use for it. In fact for many of those questions, answering in the way that is framed as positive resilience would be significant denial of reality.
  17. rvallee

    Australia: RACGP: GET for CFS

    It'll be something watching him completely change his tune once this happens and his own research is dismissed as garbage. It's easy to dump on LLMs and their potential to simply parrot what's in the literature, but that's only as long as they can't reason. Once they can do that, once they...
  18. rvallee

    Practical Recommendations for Exercise Training in Patients with Long COVID with or without Post-exertional Malaise, 2024, Gloeckl, Scheibenbogen+

    I noticed studies and headlines about this over the last few years and it's all over the place, there is zero consistency in anything. One day you can read about a study saying one thing, the next week the opposite, the next week it's about how no amount of exercise can make up for sitting 8...
  19. rvallee

    Practical Recommendations for Exercise Training in Patients with Long COVID with or without Post-exertional Malaise, 2024, Gloeckl, Scheibenbogen+

    I don't see the point in applying generic advice to specific problems. People should drink water when they're thirsty and eat good healthy food. Not for any particular reasons. They should also breathe oxygenated air that is as little polluted as possible, but not everyone has that luxury. None...
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