It's not often I can recommend an ME/CFS educational resource without reservation, but I can certainly do that for this video. It is very good, and suitable for educating health professionals.
Thanks @Ravn for your involvement in this very effective video.
60 participant; quadruple blinding
Secondary outcomes
I don't fully understand the rationale of the primary outcome. It's just seven questions on how much pain interferes with function, taken out of a larger questionnaire (the Brief Pain Inventory) that includes questions specifically on...
They give an example of a composite reference standard:
So, I think we could classify the current ME/CFS diagnostic criteria each as a composite reference standard - PEM is present; AND activity levels substantially reduced for more than 6 months; AND fatigue is present etc. The multiple...
From the Discussion, on cognitive impairment:
I'm not sure about the idea that permanent cognitive impairment is a consequence of the disease. I think a lot of us feel that the impairment fluctuates, although normal performance often can't be sustained. It would be good if there was a study...
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