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One of our members at the University and College Union (UCU), John*, used to enjoy Ironman contests, but now walking to his own bathroom is a feat of will. His resting heart rate was a remarkable 40 beats per minute (bpm), but now sitting up sees it hit 220bpm. He suffers from long Covid and his...

Long COVID is known by different names, such as post COVID-19 condition, post-COVID-19 syndrome, or post-Covid conditions, all of which include a wide range of persistent or new symptoms that develop after SARS-CoV-2 infection and last for typically more than 12 weeks to months and up to 2...

Looking forward The opportunities for further clinical research into autonomic medicine are too numerous to list. However, by pointing to a number of strategic areas, I hope to stimulate thought and catalyze ideas for potential research projects: • Well-designed epidemiologic studies are needed...

Abstract Coronavirus disease-2019 (COVID-19) is primarily a respiratory disease, however, an increasing number of reports indicate that SARS-CoV-2 infection can also cause severe neurological manifestations, including precipitating cases of probable Parkinson’s disease. As microglial NLRP3...

Abstract Background: The essential amino acid, tryptophan, is predominantly metabolised through the kynurenine pathway (KP) to generate kynurenine, an aryl-hydrocarbon receptor (AhR) pro-ligand that exerts its effects in a ligand-dependent manner. Interaction between kynurenine and the AhR is an...

Abstract We examined the effect of a COVID-19 infection on changes in exercise levels in recreational athletes in the first three months after infection, and identified personal factors associated with a larger change in exercise level and recovery time. Recreational athletes (n=4360)...

In the 90s I improved up to 80-90% by doing nothing. I got worse after taking immune modulators and never returned to baseline. I shared this with my M.E doctor and he nodded his head.

Full Title: Not all roads lead to the immune system: The Genetic Basis of Multiple Sclerosis Severity Implicates Central Nervous System and Mitochondria Involvement, 2022, Vilija G. Jokubaitis et al Abstract Multiple sclerosis (MS) is a leading cause of neurological disability in adults...

Abstract Background The gut microbiome plays an important role in autoimmunity including multiple sclerosis and its mouse model called experimental autoimmune encephalomyelitis (EAE). Prior studies have demonstrated that the multiple sclerosis gut microbiota can contribute to disease, hence...

A bacterial driver of arthritis Autoantibodies can be detected in individuals at risk for developing rheumatoid arthritis (RA) before development of clinical disease. The source of these autoantibodies, however, remains unclear. Here, Chriswell et al. identified that IgG and IgA autoantibodies...

Abstract Orthostatic hypotension affects roughly 10% of individuals with hypertension and is associated with several adverse health outcomes, including dementia, cardiovascular disease, stroke, and death. Among adults with hypertension, orthostatic hypotension has also been shown to predict...

How PEM evolves over the years would also be a significant finding. My first PEM experience was very different during the five years of PVFS. Exercise and immune modulating meds relapse made PEM worse.

Some doctors still don't understand that depression is a physical illness.

I would need to put the drawing in translate too :laugh:

Ich kann kein Deutsch verstehen

@Wonko Did you get the flu and Covid shot at the same time? I'm considering getting both this time around.

Uncovering a connection between phosphate starvation signaling and mito membrane potential. Abstract Mitochondrial membrane potential directly powers many critical functions of mitochondria, including ATP production, mitochondrial protein import, and metabolite transport. Its loss is a...

thread Thread on this Canadian Long covid clinic here: Canada: Edmonton Long covid clinic - Neeja Bakshi

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