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Exhausting search for solutions to UK’s sharp rise in tiredness "Rosalind Adam, an Aberdeen GP, and her colleagues are dealing with more people than ever reporting extreme tiredness, even taking into account their increased workload. “The thing is, we are seeing so many patients a day now,” she...

Innovative research using AI led by the University of Aberdeen aims to find better ways of managing and treating fatigue. Many people struggle with fatigue which can be the result of medical conditions like long covid, stress or simply because of modern lifestyle. This makes it difficult for...

In late 2010, an outbreak of Cryptosporidium hominis affected 27,000 inhabitants (45%) of Östersund, Sweden. Previous research shows that abdomen and joint symptoms commonly persist up to 5 years post-infection. It is unknown whether Cryptosporidium is associated with sequelae for a longer...

"Several ‘maladaptive’ cognitions and behaviors (e.g., catastrophizing cognitions and avoidance behavior) have been associated with higher symptom burden in pain syndromes and FSS such as chronic fatigue syndrome, irritable bowel syndrome and fibromyalgia" "The questionnaire was validated in...

Highlights Maladaptive cognitions and behaviors were associated with somatic symptom severity over five-year time. Associations were also found for maladaptive cognitions and behaviors and reduced physical and mental functioning. Also, within subjects cognitions and behavior may play a role...

Why is COVID life-threatening for some people? Genetics study offers clues "Baillie and his colleagues analysed data from more than 24,000 people and combined this information with data sets from around the world. They found 49 DNA sequences that are associated with becoming critically ill from...

Abstract Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype that we have previously shown1 to be highly efficient for discovery of genetic associations2. Despite the advanced stage of illness at presentation, we have shown that host genetics in patients who...

They also looked at plasma immune molecules in that study, and many of the authors were listed for both papers, so at a quick look I don't think so.

Highlights The stress-Multiple Sclerosis (MS) relationship is controversial, with low evidence. The bidirectional hypothesis was confirmed through ecological momentary assessments. Active coping was adaptive with high stress, but counterproductive with low stress. Low-trait anxiety was...

Did what I could last night to promote this conversation.

Common viral antibodies could trigger MS, research reveals “We have discovered that certain antibodies against the Epstein-Barr virus which would normally fight the infection can mistakenly target the brain and spinal cord and cause damage.” ... "EBV is one of the most widespread viruses in...

Received this response earlier today, "Hi Andy, Unfortunately we are not in a position to give an update at this time, but I will let you know as soon as there is one. All the best, Harry Harry Dayantis Head of Communications Cochrane Central Executive Team" I replied, "Hi Harry, Thank...

[Google Translated from German] Acute fatigue and exhaustion after successfully completing a sporting or professional challenge are not unpleasant per se. However, some people feel tired and underperformed in the long term. Fatigue is one of the most common complaints in the population. In...

Author Correction: Why functional neurological disorder is not feigning or malingering In the version of this article initially published, a statement of competing interests was omitted. The error has been corrected in the HTML and PDF versions of the article...

Fatigue - S3 guideline update, 2023, Kornder et al Summary background Fatigue is a common symptom in the family doctor's office, where there is often diagnostic uncertainty. Sufferers use descriptions that include emotional, cognitive, physical, or behavioral aspects. A variety of biological...

"Persons will be scheduled 3-9 months post-COVID-19 diagnosis for a clinically indicated cardiopulmonary exercise test and will have ACD, CPT, and PAX-gene tubes drawn 30 minutes before, at peak, and 1 hour after CPET testing. We expect that out of 200 COVID-19 patients, 50 patients will have...

The Post-Acute Sequelae of COVID-19 (PASC) Syndrome is a debilitating syndrome with onset three months post COVID-19 infection, marked by the presence of fatigue, headache, cognitive dysfunction, post-exertional malaise, orthostatic intolerance, and dyspnea that is clinically relevant and is at...

Sent this morning to Cochrane Press Office and IAG email addresses, "Hello, As it has now been two months since your previous response, and 39 months since the update was first announced, please can you advise me of any progress that you have made in that time. Thanks in anticipation. Andy"...

Solve Spearheads Call for New NIH Office for Infection-Associated Chronic Illness Research (IACIR) "This year, Solve is beginning one of our most ambitious advocacy projects to date — one which could alter the research landscape for ME/CFS, Long Covid, and other infection-associated chronic...

Sean O'Neill, from The Times, on Twitter promoting this petition,