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    Cellular bioenergetics is impaired in patients with CFS (2017) Tomas, Strassheim, Newton et al

    There is risk in CPET technology. It is totally unsuitable for severe patients. Its why we need a validated blood test or other investigatory marker. However a great many patients have used CPET. Nearly all recover in a week or two from what I have read. This level of risk is also found in...
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    Cellular bioenergetics is impaired in patients with CFS (2017) Tomas, Strassheim, Newton et al

    Sadly this is often the case, and nearly always the case in psychopsychiatry. With CPET data for ME or strictly defined CFS the problems are not found in sedentary controls. I do not know if this includes long term bedbound patients. Its why I think comparison of blood findings and exercise...
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    Cellular bioenergetics is impaired in patients with CFS (2017) Tomas, Strassheim, Newton et al

    It is correct to say they have not proven causation, just association, and statistically limited association at that due to the sample size. Like @Valentijn I am interested in this in comparison to repeat CPET findings. There is no question this study needs replication on a larger data set...
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    Wessely gets touchy feely

    I agree. This is a problem that is widespread in psychopsychiatry though, and the entire field has very lax standards.
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    Wessely gets touchy feely

    Actually it goes back to the 1930s at least. Its just the the term biopsychosocial was proposed in 77. Before then it had other names, and was proposed again and again. It was Engel's paper that took off, mostly because he framed it about medicine in general and not psychogenic psychiatry.
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    Cellular bioenergetics is impaired in patients with CFS (2017) Tomas, Strassheim, Newton et al

    If the bulk of the problem is in muscle etc. then the specifics of maximal respiratory capacity will be a little different to just white blood cells.
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    Bizarre sleep pattern

    I did it for years. Here is what happened. I became massively sleep deprived. Then my OI went nuts and I started passing out and falling down all over the place. Sleep hygiene might be good for mild insomnia, but its not reliable for severe circadian issues.
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    Wessely gets touchy feely

    M is just a W upside down.
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    Wessely gets touchy feely

    I think most of us are aware of that. Its one of the reasons he is dangerous.
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    Wessely gets touchy feely

    Sometimes psychopsychiatry reminds me of the Inquisition. All they need is a comfy chair.
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    Wessely gets touchy feely

    I have done the same thing, and probably will again. I don't like the sound of "one" and usually substitute "you" but the context does not always disambiguate the meaning.
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    Wessely gets touchy feely

    This is not just psychiatry, its also the other doctors who pass the patients on to psychiatry. Doctors often call patients like this "heartsink" patients, because they cannot help and they feel bad about it. How they handle this is however an issue in medical training ... failed training...
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    Wessely gets touchy feely

    Welcome to psychopsychiatry.
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    Are PWME at greater risk of cardiovascular disease & diabetes? If so, what can we do about it?

    I think the risk of diabetes and CVD is probably increased. I think the profile is different though. I think ME can look like mild diabetes if there is enough of a problem with sugar metabolism in ME. However this will increase insulin, and hence insulin resistance, over time. I suspect that...
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    Are PWME at greater risk of cardiovascular disease & diabetes? If so, what can we do about it?

    Yep, with an amendment - Dying doesn't scare me, its not having a real life that is the problem.
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    Wessely gets touchy feely

    That is my current interpretation. They have moved away from objective outcome measures when they found that all of them reliably discredit their conclusions.
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    Wessely gets touchy feely

    I think it was Peter White who made the claim that objective measures are not that important, if I recall correctly. He was defending using subjective outcomes in PACE.
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    Wessely gets touchy feely

    With psychopsychiatry very little if any is science, so yeah. With biopsychiatry at least some is science.
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    Bizarre sleep pattern

    A typical day for me. Its 6:50am here and I finally might be able to start sleeping.
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