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I sent the following email to Hilda and the New Zealand representative of Cochrane a few hours ago. It followed an email in which I thanked Hilda. She replied that she felt that her discussions with people in Cochrane were bearing fruit, and that many people within the organisation had not...

Sorry, I stuffed up with the links in the petition update. I copied and pasted 'links with text' rather than just links - they worked in the forum draft... I have corrected the links now, including on the petition site.

It could be. It might depend on the availability of clinics. In Australia, when my son was saying that he planned to go back to school the next year, he was assessed as not needing to be referred to the rehabilitation programme. The programme seemed to be reserved for young people who were...

I guess @ME/CFS Skeptic's excellent blog series on psychosomatic medicine is a good reminder that the madness has been around for a long time.

Incredible. I wonder if the patients were informed that they were being assessed for a psychosomatic overlay? If not, I think this study was unethical. The people who approved it need to take a good hard look at themselves. What right do doctors have to be telling MS patients that they are...

Prevalence of Long COVID-19 among Home-treated COVID-19 Patients in Baghdad, Iraq 2023, 2025, Majid et al Authors from Department of Community Medicine, College of Medicine, Al-Mustansiriya University, Baghdad, Iraq and the Iraqi Ministry of Health

I have one reservation about Hilda's otherwise excellent blog, and the issue is also present in the #MEAction announcement that @Nightsong has just posted: The focus is on the outdated ME/CFS criteria and the existence of PEM. It's all very face saving to the Larun et al authors, and Cochrane...

Don't miss Hilda's blog post, link in my post above. It sounds as though the IAG basically never got a look in for the approximately 5 years it existed. The writing group finished its draft and gave it to the Editorial Group who did nothing apart from probably realising that the new review...

Open letter from the IAG to Cochrane: https://hbprojecttalk.wordpress.com/2025/01/24/independent-advisory-group-open-letter-to-cochrane/ Hilda's blog post: https://absolutelymaybe.plos.org/2025/01/24/when-journal-scientific-society-and-community-values-clash/ This was posted on the talk page...

In Results, it is reported that That matches Table 1 where the demographic data is reported and the reported numbers of participants whose data is included in the model. Also in Results, it is reported that Those numbers are quite different, and the reason for the difference is not clear. It...

I didn't find any information in the Methods section about whether the controls had had a Covid-19 infection/ time since Covid-19 infection. And the cohorts are not matched well on sex. The percentage of females in the Long covid group was 67.6%. The percentages of females in the healthy...

A German study of post-covid syndrome with a good sized sample of nearly 1000 people with PCS found no differences in (presumably serum) cortisol or ACTH levels. 11.6% of people were assessed as meeting ME/CFS criteria (I'm not sure which one) Persistent symptoms and clinical findings in adults...

There's some interesting results reported there that make this paper worth a closer look. It has a good sample size (982 PCS and 576 age and sex matched controls. Recovery - not great 6-12 months to be observed as having PCS, then a 3 to 14 month followup period, at the end of which recovery...

SULT1A1 was another one new to me. sulfotransferase family 1A member 1 Seems to have a bit to do with the liver and de-toxification of compounds. It seems as if it is effectively a switch for a whole range of molecules - the sulfonation makes them active. A 2017 paper by Kathleen Light et al...

OSM is one that I can't recall having seen before Oncostatin M (OSM) is a cytokine that can affect the expression of chemokines in the skeletal muscle and intestinal mucosa. OSM can affect the expression of chemokines in skeletal muscle after exercise. For example, OSM can increase the...

Ha, I see that I thought that 2022 paper had had lab problems even back then. This 2025 paper is definitely more aligned with common findings in LC and ME/CFS. Comments from the 2022 paper thread: My comment there reminds me that the healthy controls may also show some raised chemokines for...

"CXCL8 is the most potent human neutrophil-attracting chemokine and plays crucial roles in the response to infection and tissue injury. CXCL8 activity inherently depends on interaction with the human CXC chemokine receptors CXCR1 and CXCR2, the atypical chemokine receptor ACKR1, and...

According to the chart in the graphical summary, the highest ranked proteins differentiating LC from HC were CXCL8 (IL8) CCL7 CXCL11 OSM SULT1A1 CCL3 LC differed from MISC by having higher levels of CXCL5, but lower levels of IL-10, CXCL-9 and CXCL10.

An Italian team, I don't know if we have seen previous work by this group? Edit - there's this one which appears to be the literature review ahead of this work Susceptibility of SARS-CoV2 infection in children, 2023, Cotugno, Buonsenso et al. Also Autonomic cardiac function in children and...

That looks very interesting. Unfortunately, there is a paywall. If you click though on the 'Link' link, there are some teasers. The PCA analysis looks very impressive. It's fuzzy for me in the original and even fuzzier in a screen shot, but worth copying here I think. The Long covid are the...