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This figure seems to show the main results. Doesn't look like a large difference.

With 10 severe and 10 mild ME/CFS patients, the study seems to small to conclude anything unfortunately.

Quote from the study:

That says a lot about Leif Kennair.

Looks like this is the data presented by Cook during a CDC call last year, discussed here: https://www.s4me.info/threads/dane-cooks-analysis-of-exercise-data-of-the-cdcs-mcam-study.22191/ I think it is rather interesting. In the past exercise studies of ME/CFS reported lower VO2Max, an...

Some major limitations: It's retrospective, asking patients how they felt before infection when they already had the infection. It had no control group without infection and only 1 in 4 people contacted responded. I'm a bit frustrated that we still haven't got a decent prospective study that...

But I don't think the whole process they started with setting up an advisory board with representation from patient organisations is described in that rulebook. And it has never been the main issue that critics of the review asked for (they simply wanted errors to be corrected). I think that...

Yes, Seyle and stress might be another episode to focus a blog post on. He wrote the following review on the cover of the book getting well again by Carl Simonton. There are other pioneers of 'psychoneuroimmunology' who show up in internal tobacco documents and seem to have received funding...

There are still a lot of these stories that we need to look at it, like ulcers and stress, type A and heart disease, ulcerative colitis, skin disease etc. So I think we first will try to keep going and only afterwards we might see if more can be done to spread the message more widely.

Weird that this is published in a newspaper because there is no actual news story here. It seems that it is part of a series on how to move where they write advise on exercising for all sorts of illnesses.

The remarkable testimony of Richard Renneker In previous blog posts, we took a deep dive into the problematic psychosomatic literature on cancer. In the 1950s, psychoanalytic researchers argued that people developed cancer because they repressed their emotions or, in the case of women with...

This looks like another example in surgery where non-blinded trials with bad controls reported positive results until a proper study was set up. Bhatt et al. 2014. A Controlled Trial of Renal Denervation for Resistant Hypertension BACKGROUND Prior unblinded studies have suggested that...

Looking at patients who meet multiple case definitions might not be such a bad idea given the problems with the Fukuda criteria. So it's mostly the term "severe ME/CFS" for this group that is misleading. So perhaps we could come up with an alternative term that describes it better and then...

This has been noted already, but in this study of the 238 students who got Infectious Mononucleosis, 48 or 20% had a diagnosis of ME/CFS after 6 months. This is double from the 10% that has previously been reported. I think it's also a bit surprising that only 18 out of those 48 (37%) met more...

The paper states: Perhaps the most notable finding is that it is quite difficult to predict who will get ME/CFS after EBV-infection, even if you have measures of symptoms, cytokines and the severity of infection. On the other hand, we might simply need bigger samples.

I suppose it will always be in the back of our mind.

The fact that they decided to unpublish it suggests they didn't take a close look at it when they published it. And that's a a bit strange because LP is strongly discouraged in the NICE guideline.

I wonder how such an article ended up on the BJGP website in the first place. Someone influential who favours the Lightning Process must have pitched it, I guess.

The Lightning Process Package costs 650 pounds per person, the website says. It mostly consists of "Three consecutive half-day training (3-5 hours per day) these are usually held in small groups of 3-5 people." So if you take 3 persons per group, then an LP coach can make 650 pounds a day by...