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WHO releases clinical case definition for post #COVID19 condition or ‘#LongCovid’ in children and adolescents What it says on the tin. Don't get too excited.

Only one young person out of the 215 was recorded as having depression; only one was recorded as having anxiety. Both, or perhaps the same person, had moderate disease. Only one person out of the 215 was recorded as having behaviour change. Quite a lot of these children had severe Covid or...

Prospective studies like this have tremendous potential to tell us about recovery rates. But, this is a 'tertiary' hospital and the abstract and method does not make it clear how the children came to be assessed. It therefore seems likely that this sample was not an unbiased population sample...

Either the position wasn't filled, or that jobs website doesn't update its content. Hopefully the former. Link to the advertisement on the university website.

I want this idea of reduced retinal capillaries to be true. But the differences between the post-covid-19 syndrome results and those of the controls seems so small as a percentage of the total numbers: They had to adjust for age and gender. Figure 1 just doesn't look that convincing, and I'm...

Looks like a carefully done study, with the authors having a decent understanding of ME/CFS. The following is some googling, to understand what CD68+ and CD169+ macrophages do, and to see if they have been mentioned in connection with ME/CFS before: About CD68+ "CD68 is a heavily glycosylated...

This looked worth noting. Until they actually looked, there wasn't necessarily much to indicate that there was organ impairment: I guess a question is, did people have these organ impairments before Covid-19 and the impairments predisposed the individual to post-covid symptoms? Or did Covid...

Very true. The study found quite a high rate of detectable organ impairment. There are two things to consider: 1. What is the rate of detectable organ impairment in the general population? Perhaps issues are being picked up that are not related to Covid-19. 2. Selection bias. Some of the...

A paper that seems to be the product of this study Internet-delivered [CBT] for chronic fatigue among adolescents with a chronic medical condition, 2023, Nijhof, van de Putte, Knoop et al The paper is one of the worst I have seen, and that is saying something.

Nice linking @bobbler. Authors of this 2023 study Linde N. Nijhof Sanne L. Nijhof, Elise M. van de Putte, Jan Houtveen, Joris M. van Montfrans and Hans Knoop Doing some linking of my own, I see that we have a tag for fitnet-plus, which links though to this trial registration from about five...

So, I'm procrastinating, and finding out the utility of a randomised waiting period in an unblinded trial with only one participant proved too interesting Re ME/CFS: So, there were 9 participants, but for whatever reason, they aren't going to tell us about that. Hmm. Perhaps some risk of...

It's bizarre, isn't it. Large surveys with patients reporting that CBT doesn't treat fatigue; large numbers of patient charities reporting that CBT doesn't treat fatigue - all these are worth nothing. But the case study of one person who reports reduced fatigue but shows no significant...

Sigh. And still the victim-blaming nonsense keeps coming. Subjective Traumatic Outlook Questionnaire 1. Looking on your condition, do you feel that you suffer from psychological trauma? 2. Looking back, do you see a fracture line between your life before the event and after the event? 3. Do...

This case study has the problems that case studies have - n=1 and confounding factors of the RA and vaccinations. Tocilizumab reduces the effectiveness of the immune system, the woman was immunocompromised. Still, the discussion in the case study is interesting. Nirmatrelvir/ritonavir is...

When I read things like that, I wonder who is funding that sort of work which, as @Shadrach Loom says, is really about making the diagnosis of something very similar to hypochondria and hysteria more palatable to patients. The first author is based at Radboud University Medical Center, Radboud...

Brilliant poem.

:rofl: Me too. Alibaba

I haven't read much of the paper yet, but it looks really useful. Good reading for any peer reviewer or patient representative in a research team. There's content there that would be useful for people about conducting research well and being critical about scientific papers. Also good for...

Drawing on comments made by @Robert 1973 and @bobbler above: In any future replication, as well as extending the study out further in time, it might be useful to look at differences upon waking from a person's primary sleep. Perhaps there is a significant difference in the efficiency of sleep...

I think, at the very least, that a lot of the people involved thought it was a genuine process. I am sure that Hilda believed that it was genuine and I think she thought that she was in control of it. What I can't understand is why she and others involved who care about people with ME/CFS have...