Search results

I agree, most of the differences do not look major. I think it is a pity that the authors keep referring to 'profound' differences when it all looks pretty marginal. I don't think one can draw any very specific conclusions from the findings so far. It would have been interesting if this study...

It's a very odd and perfunctory report. Large atypical T lymphoblasts do not sound much like inflammation. I wonder if by chance there was a low grade local T lymphoproliferative disorder, although T cell lymphoproliferation is rarely benign. One wonders why a more extensive formal pathology...

Has anyone seen the text of the paper? The abstract mentions chronic inflammatory change but in the spleen that is pretty meaningless. The spleen is normal full of inflammatory cells - that is where half of them normally live. If the spleen had been traumatised ten days earlier you would expect...

There is something a bit spooky about the logic here. If I look at points 1-13 and think what I would have answered in the spring when my sciatica was rally bad I would have scored pretty near 4x13=52. I went to a neurosurgeon. After all these statements I would put in brackets (R) for realism...

I can't get excited about reading this stuff on Christmas Eve. But is there any sign that they realise that the feasibility trial has been found out, as a simple cheat? I guess one could argue that it is the proper thing to do to produce a published report even if the research is too poor to...

This is what psychologists think people need to cheer them up on Christmas Eve. Beggars belief really.

I have not yet managed to see the questions in the questionnaire but do they ask: 1. Do you have an exaggerated response to pain, compared to normal people? 2. Do you ruminate on pain more than normal people do? 3. Do you get more emotional about pain than normal people? Because if not, how do...

How do you get a 'should' out of an observational meta study?

Presumably T cell clones educated during infancy are still around to protect against measles in old age but they Amy have undergone many divisions during that time I guess. Immune responses tend to get fixed in memory mechanisms that are pretty much life long and most, although not all, immune...

If you mean that man (again) on the wireless I think he died in 1949.

Depressive states are normally divided into reactive and endogenous and the two tend to be very different in presentation although in both cases despair is often expressed. I do not have any hard information but I have come across much to suggest that PWME have endogenous depression more than...

The problem is, @Andy, as you can see above, that it is not clear that you have to scroll down to find the boxes to tick. There is just a question and 'exit'. Savvy people may see the scroll bar on the right but I certainly didn't. On your picture above the bottom line of text is slightly...

Yes, I think it is in the thymus. I presume that bone marrow-based progenitors do not give rise to T cells. Edit: reviews on this are a bit confusing, because bone marrow stem cells give rise to T cell precursors early on. I guess the question is whether the bone marrow stops producing T...

I agree with @Kitty. If the ordinary blood test do not show anything, genetic testing will tell you nothing. Genetic tests might tell you why your blood tests are abnormal, if they are, but if they are normal then the genetics will be irrelevant. Genes can only have an effect through the...

I think new T cell genesis just drops right off in adulthood.

Now I see that you have to scroll down, but there is nothing on the original image to indicate that. The window that comes up shows no options and no instructions

The window does not have any yes or no or paces to click for me @Andy And I don't have ME/CFS

I went to https://mebiomed.org.uk/get-involved/ and could not find anywhere to click on other than an x after which it said thank you for taking the survey!

Aha

I read that as The Many Faces of Sigmund Freud - excerpt adapted from "Freud in the Lab" .......must have been a Fraudian slip.