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  1. Jonathan Edwards

    Hypnosis and hypnotherapy (also Rapid Transformational Therapy)

    I am afraid this is a complete misconception. Nothing new was discovered about the relation of earth to sun by space flight. I am not sure where you got that idea from. Copernicus's contribution was to say that if we consider the motion of sun and earth taking sun as centre then the...
  2. Jonathan Edwards

    Hypnosis and hypnotherapy (also Rapid Transformational Therapy)

    Sorry but it's completely wrong. This is nothing to do with not fitting previous theories. It is that psychological theories are too vague to be properly testable and most of the time contradict themselves anyway. Copernicus and Galileo had precise tests and results. Maybe read Karl Popper, who...
  3. Jonathan Edwards

    Hypnosis and hypnotherapy (also Rapid Transformational Therapy)

    How could anyone know any of that if we know little about the subconscious mind? Aren't these just the myths surrounding hypnotherapy? Theories like this are not reliably testable so should have no place in clinical medicine. Something we have been trying to drum into the skulls of the BPS...
  4. Jonathan Edwards

    Closed UK: DecodeME updates, was recruitment thread.

    I don't know the rules about this but am tempted to assume there are none and that the DecodeME team could contact directly, indirectly or however anyone can think of. I don't really see any conflict of interest in just asking organisations with communication systems to help spread the word...
  5. Jonathan Edwards

    Closed UK: DecodeME updates, was recruitment thread.

    Versus Arthritis are interested in a wide range of things. They certainly fund widespread pain studies, muscle disease and so on. It may be that their remit is more or less that of rheumatology, which has quite wide borders. The MRC obviously has a very wide remit but in terms of charities I am...
  6. Jonathan Edwards

    Protocol: Randomized-controlled Trial of Immunoadsorption (IA) in Patients With CFS Including Patients With Post-COVID-19 CFS, 2023, Burock

    Primary outcome is Chalder fatigue scale. If this is genuinely blinded it may not matter if the outcome measure is suboptimal.
  7. Jonathan Edwards

    Closed UK: DecodeME updates, was recruitment thread.

    I think it is a pretty big achievement to get 9,000 samples in. I always thought that it would be reasonably straightforward to get the first half of the number wanted and that getting the second half would need some pushing. Is now the time to try other avenues for publicity. I am wondering...
  8. Jonathan Edwards

    Circulating microRNA expression signatures accurately discriminate [ME] from fibromyalgia and comorbid conditions 2023 Moreau et al

    I find this very hard to interpret but I suspect that the findings in figure 2 of high levels in ME and low in FM and middling in normals is just an artefact of them looking for the biggest differences between ME and FM - which are more or less bound to show that pattern or near enough. To me...
  9. Jonathan Edwards

    UK - Job coaches at GP surgeries to push unemployed over-50s back to work

    This is presumably because a number of very very rich people who have to work until ten o clock at night moving money around for very very very rich people are peed off because some very poor people are getting a little bit of cash to pay their bills while they go to food banks. How come that...
  10. Jonathan Edwards

    Towards evidence-based and inclusive models of peer support for long covid: A hermeneutic systematic review 2023 Mullard, Greenhalgh et al

    Let's face it, this (hermeneutics) is just hard core drivel yet again. Unless you have a fairy frock and beads and can dance around in those two overlapping circles in bare feet and chant creativity you haven't a chance. The more people witter on about applying common sense the more likely...
  11. Jonathan Edwards

    No Causal Effects Detected in COVID-19 and ME/CFS: A Two Sample Mendelian Randomization Study 2023 Xu et al

    This doesn't seem to make any sense to me. All they seem to be saying is that if Covid-19 causes ME then they haven't been able to find any clues as to what factors are critical in causation. Not that there is no causation.
  12. Jonathan Edwards

    Covid-19 vaccines and vaccinations

    I think it was done in mice. They like their vaccinations before breakfast so they can do a bit of scratching. I personally like a vaccination either at 11.30 am so that I can get home for lunch before it starts to itch - or just before tea time. I can't see health services going in for the...
  13. Jonathan Edwards

    Stress-Induced Transcriptomic Changes in Females with ME/CFS Reveal Disrupted Immune Signatures, 2023, van Booven et al.

    All I can see in the abstract and conclusions are vague suppositions about regulation of some unspecified immune response. A decent paper gives you some data, without too much interpretation. If there are interesting results here, why not tell us?
  14. Jonathan Edwards

    BMJ Opinion “Functional disorders”: one of medicine’s biggest failures, 2023, Smith

    As far as I can see there are two Richar Smiths, both involve in political pressure groups on health. I had thought it was the other one but it looks as if it is the one who was a doctor and once editor of BMJ. He has a reputation for callous commentary - in relation to cancer in particular.
  15. Jonathan Edwards

    Thesis Thesis: Investigating the Genetic and Immunological Aetiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2022 Dibble

    The abstract is soberingly impressive. I hope Joshua goes on to find the needle in the haystack. In the meantime, this is useful work precisely because the findings were negative.
  16. Jonathan Edwards

    Do Human Endogenous Retroviruses Contribute to Multiple Sclerosis, and if So, How?, 2019, Morris et al

    This all looks like complete nonsense. In line with previous papers from these authors. Is it of any interest to an ME forum? I cannot quite see why.
  17. Jonathan Edwards

    Pulse: Long Covid training course - Dr Shah

    Now, if we are sure that myalgia is really down to Long Covid, then we can signpost them to information and self-management services. I do believe that most areas now, certainly in England, have community Long Covid clinics. And so, it's really helpful to refer these patients to these settings...
  18. Jonathan Edwards

    List of rare and uncommon diseases: differential and mis – diagnosis in ME/CFS

    I was talking about fringe theories rather than 'fringe cases'. What I mean by a fringe theory is something that most people who look carefully would judge to be vague or incoherent speculation. Highlighting rare diseases makes sense. Highlighting academic babble doesn't.
  19. Jonathan Edwards

    List of rare and uncommon diseases: differential and mis – diagnosis in ME/CFS

    I am doubtful that there is justification for including Empty Sella Syndrome specifically. Low pituitary function of any cause might produce symptoms misdiagnosed as ME. (I doubt ESS would produce symptoms for other reasons.) The paper quoted suggesting that changes in CSF pressure may be...
  20. Jonathan Edwards

    BMJ Opinion “Functional disorders”: one of medicine’s biggest failures, 2023, Smith

    As far as I can see Richard Smith is not a doctor but a health economist. The chanting of the BPS mantras seems to be second hand. Embodied cognition isn't even a theory. It is a sort of pseudoscientific incantation. When one sees this garbage trotted out in this blasé way by some one doesn't...
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