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Just that a report like that screams 'Hi, guys, here's a bogus report for you'. If a test is not suitable for clinical use you do not release it for clinical use. You don't just add a 'disclaimer'. Rather than the best you can get this may well be the worst.

Chiefly because the immune system isn't inside the brain, even if sometimes it has effects on the brain.

I am pretty sure this is pseudoscience. Intracellular electrical capacity in lymphocytes means nothing at all as far as I am aware. Note that the form says that the test is only for research purposes and not suitable for clinical use. I do hope that members can see that this tells us nothing...

Maybe but that paper basically says: Results: LongCovid symptoms bore no relation to FND, being rather things like headaches and ageusia, and try as hard as we might we couldn't find any other way to make any coherent link between the two because it wasn't even looked for. This is just a load...

An honest attempt at gathering data has to include making sure the results are not misleading. If the basics of scientific method are not clear to you @glennchan you might do well to steer clear of all of this. I suspect pretty much everybody on this forum is going to disregard everything you...

I have not gone through the paper in great detail but like Hutan I think there may be problems with it. One thing that is strange is that only one out twenty six cases was male and there is no reason why any genuine EDS group should show that. The major problem I see is that the diagnosis of...

What TG says in the tweets seems reasonable to me. She is surprised by the lack of literature on microclots if they are an important finding. I don't think the lack. of literature is likely to be due to bias - just scepticism amongst haematologists that there will be anything significant to find.

I have never heard of BMC Rheumatology as a journal. Skimming, this looks like an article pushing a politically correct point about patient symptoms in a common sense vacuum. There is a specific problem with CRP for treatments that lower CRP irrespective of any effect on disease. I doubt that...

I think the point is that there is a group of people with striking neurological symptoms like seizures or tremors or twisting movement disorders for whom no structural neurological change can be found who can reasonably be put into a diagnostic category. Maybe it should be called 'people with...

FND refers to a real group of people, mostly with seizures and movement disorders. It may be a silly diagnosis but the people and symptoms are real. As far as I know LongCovid bears no resemblance. Shure seems to be well into pottyland disinformation.

The mean age of ME/CFS patients dying from heart failure, 58.7 years, was significantly lower than the age of those dying from heart failure in the general US population, 83.1 years I wonder if this corrects for the fact that very few people over 65 appear to admit to having ME/CFS for...

CD68 is a general macrophage marker. CD169 probably equates to active scavenger macrophages with antigen-presenting capabilities. I am not sure that it tells us more than that macrophages have recently been called in. it may do. I would be interested to know what these muscles look like stained...

Studies of this sort are likely to accrue all sorts of biases in the groups of patients studied, depending on what clinics they were drawn from and on and on... I have never heard of this claim about malaise for 24hrs but it doesn't sound to me particularly suggestive of PEM. If you have an...

I worked as a rheumatologist for over thirty years without ever doing an exam in rheumatology - as did we all in 1975. The UK public have always been too trusting I suspect.

I get the impression that this paper is a bit like a family of stick insects that decided to go for a walk where a group of chameleons had decided to make a stake out.

Suggests that aerobics is useless but I doubt one can conclude anything since it is unblinded.

This looks like serious disinformation from a certain Dr Jennifer Curtin, associated with Kaufman and Chheda?

I had a quick look. I cannot see how one can really draw any conclusions without any control data. Goodness knows what caused what here.

Simon Wessely might well have something to do with this I guess. The mental health benefits of working in the NHS are so great that everyone is leaving. Redeploying people is surely the business of employers, not doctors. This will be yet another incentive for GPs to quit. It is hard to see how...

We need a deeper understanding because the ideas Iwasaki and Putrino are suggesting are just what anyone could have made up from the start and don't go anywhere. It is a pity that biomedical science now has this parallel empty vessel clanging going on alongside meaningful research.