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  1. rvallee

    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    Their "masks don't work" review, however, very popular in conspiracy crowds. I keep seeing it used as "definitive evidence", despite Cochrane actually coming out to do damage control and insist it doesn't mean that. People who would otherwise never trust anything out of Cochrane...
  2. rvallee

    The Chrysalis Effect

    Hmmm... given the wording, I wonder if this actually falls under the rules here. They're not marketing this as a treatment for ME, they're marketing this as a training program for, uh, practitioners, I guess, to enable their clients to "enable recovery success" from ME. The clients aren't...
  3. rvallee

    WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et al

    Ayup. There is some muscle mass loss, but it's only anything extra from the base mass, what is gain from using and growing them. When flexing, it doesn't seem any less than it was. I've lost a lot of weight in recent months so they are especially easy to see, still as well-defined as ever. The...
  4. rvallee

    Comparison of semen parameters in the same patients before and after diagnosis of COVID-19, 2023, Cakir

    The before and after comparison is much more valuable than this, as unfortunately, there is no guarantee that this means anything. It's really as if medicine is unable to accept what asymptomatic infections mean, what they imply and especially how the policy of mass reinfections basically...
  5. rvallee

    “Inverse Vaccine” Could Treat Multiple Sclerosis and Range of Other Autoimmune Diseases

    The paper. Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses https://www.nature.com/articles/s41551-023-01086-2 Inducing antigen-specific tolerance during an established immune response typically requires non-specific immunosuppressive...
  6. rvallee

    “Inverse Vaccine” Could Treat Multiple Sclerosis and Range of Other Autoimmune Diseases

    Wow, this would be incredible if it works. "All" it would take is to identify which antigens are being marked for attack and simply deactivate. Still leaves a lot of work but this could be revolutionary, make autoimmune diseases treatable, even curable.
  7. rvallee

    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    Not even a word from Bastian makes her whole involvement, or lack thereof, seem even worse. She is the face of this now, she is supposed to be independent from Cochrane. Cochrane has a lot to deal with here, they will consult with their lawyers and no doubt do a lot of coordination with the very...
  8. rvallee

    News from Germany

    Ah yeah that's what I meant. Poorly phrased, just about what he meant by "more". And for what it's worth: Should probably assume that this means through the EU, as there is a proposal for major funding and Germany is the biggest player in the EU.
  9. rvallee

    WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et al

    The NIH are highlighting this paper on their News & events. Protein may be linked to exercise intolerance in ME/CFS https://www.nih.gov/news-events/nih-research-matters/protein-may-be-linked-exercise-intolerance-me-cfs At a Glance A study suggested that high levels of a protein may reduce...
  10. rvallee

    News from Germany

    I think those are related, in that 15M Euros have been made available, and Lauterbach wants 60M more:
  11. rvallee

    Long Covid in the media and social media 2023

    BMJ: What happens inside a long covid clinic? https://www.bmj.com/content/382/bmj.p1791 7 September 2023 Shows how there has been zero progress, despite us having been right all along. At least some are moving away from the reconditioning model, advising pacing with the caveat that it's not...
  12. rvallee

    Long Covid in the media and social media 2023

    Maybe it was poison. Maybe it wasn't. You can get doctors to know about things like LC, but you can't really make them understand it. "Up to 6 months", for which of course there are plenty of claims as such, from eminent sources. What a joke. And apparently they did joke around, until they...
  13. rvallee

    Trial Report Tonix's Long COVID Drug Fails to Meet Midstage Trial Goal

    Drug trials have different requirements than behavioral stuff. In that they have actual requirements. And standards. And some accountability. Because rich people's money is involved. It's easy to see why there are strong incentives not to report them, given the drop on their stock price...
  14. rvallee

    Functional Neurological Disorder (FND) - articles, social media and discussion

    cost-effective lack of accessible treatment Hmm. I don't think they gave this one much thought. Are they imagining that if they could devise treatments they would be cost-effective? That's just imagination. Like if wishes had wings, we could fly, presumably cost-effectively. Or are they...
  15. rvallee

    A Case Series of Transgender and Gender-Nonconforming Patients in a Pediatric Functional Neurologic Disorder Clinic 2023 Wilkinson-Smith et al

    They certainly increase the risk of being labeled as such. That is correct. Especially given how bigotry and prejudice intersect, and those are issues featuring both by the boatload. But that is not the same thing at all, what with there being no test for it, and applying a diagnostic process...
  16. rvallee

    Long Covid in the media and social media 2023

    Twitter thread on a FDA stakeholder meeting on Long Covid:
  17. rvallee

    Long Covid in the media and social media 2023

    Threads, the Twitter alternative made by Facebook/Meta, is censoring several terms related to Covid. It appears to include words related to illness, as well as Covid, which would naturally include Long Covid. Searching for those simply comes off as "no results". It appears to be a general...
  18. rvallee

    Long Covid in the media and social media 2023

    Letter to the editor: What Long COVID Prevention Strategies Suggest About Its Pathophysiology https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad466/7264811?login=false Lao-Tzu Allan-Blitz, Howard Hu, Jeffrey D Klausner Our hypothesis is analogous to the setpoint hypothesis in...
  19. rvallee

    Review Non-Pharmacological Treatment of Autonomic Dysfunction in Parkinson’s Disease and Other Synucleinopathies, 2023, Palma, Jose-Albertoa;Thijs, Roland

    Almost nothing that they propose is feasible to put through randomized trials, since they are never conclusive, simply do not allow for competent evaluations. They are basically dozens and dozens of small adaptations, which feature such doozies as "sitting, rather than standing", which when...
  20. rvallee

    German Government announces new funding guidelines for ME/CFS

    Meh. The entire model is completely outdated. Journals aren't even needed, they add no value, and it's clear that the approach of peer review before publication doesn't work, plenty of invalid stuff makes it through and it's mostly treated as a "it's published, can't be any flaws in it, lalala...
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